Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
| ▸ | FER | P16591 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21795060 | 0.72 | ALOX5 (0.44) | ALDH1A1HTTHSD17B10CYP3A4TDP1 | |
| SCHEMBL13469502 | 0.71 | ALDH1A1 (0.52) | ALDH1A1HTTHSD17B10CYP3A4TDP1 | |
| SCHEMBL1711500 | 0.71 | ALDH1A1 (0.56) | ALDH1A1HTTHSD17B10TDP1KDM4E | |
| SCHEMBL22492411 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HTTHSD17B10CYP3A4TDP1 | |
| SCHEMBL29789856 | 0.71 | ALDH1A1 (0.51) | ALDH1A1HTTHSD17B10CYP3A4TDP1 | |
| SCHEMBL1337683 | 0.71 | ALDH1A1 (0.59) | ALDH1A1HTTHSD17B10KDM4EHPGD | |
| SCHEMBL16431296 | 0.69 | ALDH1A1 (0.59) | ALDH1A1HTTHSD17B10CYP3A4TDP1 | |
| SCHEMBL22915137 | 0.68 | TP53 (0.52) | ALDH1A1HTTHSD17B10TDP1KDM4E | |
| SCHEMBL22915160 | 0.68 | TP53 (0.52) | ALDH1A1HTTHSD17B10TDP1KDM4E | |
| SCHEMBL22915214 | 0.68 | ALDH1A1 (0.50) | ALDH1A1HTTHSD17B10CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4091081-A | — | — | None | — | — | JP | disclosed |
| JP-H0491081-A | NEW 1,2-DIHYDRO-4H-3,1-BENZOXAZIN-4-ONE DERIVATIVE AND ITS PRODUCTION | KISSEI PHARMACEUT CO LTD | 1992-03-24 | — | — | JP | disclosed |