Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MPL | P40238 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TOP2A | P11388 | 1/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830875 | 0.99 | MAPT (0.55) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL3641684 | 0.76 | CNR2 (0.50) | MAPTKMT2AALDH1A1LMNACNR2 | |
| SCHEMBL8650450 | 0.75 | MAPT (0.62) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL8980297 | 0.72 | KMT2A (0.59) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL24797141 | 0.72 | ALDH1A1 (0.42) | MAPTKMT2AALDH1A1LMNAMPL | |
| Sulisobenzone SCHEMBL27776281 | 0.72 | LMNA (0.97) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL3824293 | 0.71 | CA1 (0.49) | ALDH1A1LMNATSHRKDM4EHPGD | |
| Sulisobenzone SCHEMBL16330 | 0.70 | LMNA (1.00) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL9141423 | 0.70 | KMT2A (0.60) | MAPTKMT2AALDH1A1LMNAMPL | |
| Sulisobenzone SCHEMBL167868 | 0.70 | LMNA (1.00) | MAPTKMT2AALDH1A1LMNAMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4338398-A | — | — | None | — | — | JP | disclosed |
| JP-H04338398-A | DIPHENYLMETHANE DERIVATIVES, ITS PRODUCTION AND REAGENT CONTAINING THE SAME FOR DISPLACEMENT OF IODOTHYRONINES FROM PROTEIN BINDING IODOTHYRONINES | BOEHRINGER MANNHEIM GMBH | 1992-11-25 | — | — | JP | disclosed |