Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MPL | P40238 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL9618535 | 0.99 | MAPT (0.54) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL3641684 | 0.77 | CNR2 (0.50) | MAPTKMT2AALDH1A1LMNACNR2 | |
| SCHEMBL8650450 | 0.76 | MAPT (0.62) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL8980297 | 0.73 | KMT2A (0.59) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL24797141 | 0.73 | ALDH1A1 (0.42) | MAPTKMT2AALDH1A1LMNAMPL | |
| SCHEMBL3824293 | 0.72 | CA1 (0.49) | ALDH1A1LMNATSHRKDM4EHPGD | |
| SCHEMBL9141423 | 0.71 | KMT2A (0.60) | MAPTKMT2AALDH1A1LMNAMPL | |
| Sulisobenzone SCHEMBL167868 | 0.71 | LMNA (1.00) | MAPTKMT2AALDH1A1LMNAMPL | |
| Sulisobenzone SCHEMBL16330 | 0.71 | LMNA (1.00) | MAPTKMT2AALDH1A1LMNAMPL | |
| Sulisobenzone SCHEMBL9474717 | 0.71 | LMNA (1.00) | MAPTKMT2AALDH1A1LMNAMPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | claimed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | claimed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | claimed |
| EP-2010294-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2009-01-07 | — | — | EP | claimed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | claimed |
| CN-115484927-A | Method for producing hydrophilic organopolysiloxane gels | 瓦克化学股份公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-109562037-B | Thickened, transparent, salt-rich composition, lightening method thereof and use thereof in cosmetics | 化工产品开发公司SEPPIC | 2021-11-23 | — | — | CN | disclosed |
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| EP-2010294-B1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2015-12-02 | — | — | EP | disclosed |
| US-7906684-B2 | Antioxidants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-03-15 | — | — | US | disclosed |
| US-20090246158-A1 | ANTIOXIDANTS | MERCK PATENT GESELLSCHAFT (DE) | 2009-10-01 | — | — | US | disclosed |
| EP-2010294-A1 | ANTIOXIDANTS | Merck Patent GmbH (DE) | 2009-01-07 | — | — | EP | disclosed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | disclosed |
| WO-2007121845-A1 | ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2007-11-01 | — | — | WO | disclosed |
| EP-0498240-B1 | Derivatives of diphenylmethane, process for their preparation and their use in supplanting iodothyronines and the proteins binding them | BOEHRINGER MANNHEIM GMBH (DE) | 1994-12-07 | — | — | EP | disclosed |
| EP-0498240-A1 | Derivatives of diphenylmethane, process for their preparation and their use in supplanting iodothyronines and the proteins binding them | Roche Diagnostics GmbH (DE) | 1992-08-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090246158-A1 | ANTIOXIDANTS | LPO, GPX1, GPX4 | MAPT 1568/4885KMT2A 2864/4885ALDH1A1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.