SCHEMBL9618707

SCHEMBL9618707

Cc1cc(C(C)C)cc(C(C)C)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.43
GABRB2 P47870 1/20 0.43
FABP4 P15090 4/20 0.42
FABP3 P05413 2/20 0.42
LMNA P02545 5/20 0.41
FABP5 Q01469 1/20 0.41
GABRB1 P18505 1/20 0.37
ADRA1A P35348 3/20 0.36
CHRM1 P11229 2/20 0.36
HTR2B P41595 2/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX15 P16050 1/20 0.36
MAOA P21397 1/20 0.36
TBXA2R P21731 1/20 0.36
FKBP1A P62942 1/20 0.35
PTGS1 P23219 2/20 0.34
TRPA1 O75762 2/20 0.34
CACNA1C Q13936 1/20 0.34
ALDH1A1 P00352 1/20 0.33
PTGS2 P35354 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12533349 0.85 HTR2B (0.48) GABRA1GABRB2FABP4FABP3LMNA
SCHEMBL5790732 0.85 GABRA1 (0.50) GABRA1GABRB2FABP4FABP3LMNA
SCHEMBL17125221 0.79 LMNA (0.42) GABRA1LMNAGABRB1ADRA1ACHRM1
SCHEMBL15934965 0.79 LMNA (0.38) GABRA1GABRB2FABP4FABP3LMNA
SCHEMBL10548502 0.76 LMNA (0.43) GABRA1GABRB2LMNAGABRB1ADRA1A
SCHEMBL9064418 0.76 GABRA1 (0.46) GABRA1GABRB2FABP4FABP3LMNA
SCHEMBL15132879 0.76 EIF4A3 (0.35) GABRA1GABRB2LMNAADRA1ACHRM1
SCHEMBL17125232 0.76 LMNA (0.39) GABRA1LMNAGABRB1ADRA1ACHRM1
SCHEMBL10784694 0.76 CYP3A4 (0.62) GABRA1GABRB2LMNAGABRB1ADRA1A
SCHEMBL26890853 0.76 LMNA (0.39) GABRA1LMNAGABRB1ADRA1ACHRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4352735-A None JP disclosed
JP-H04352735-A 2,6-DICHLORO-3,5-DIISOPROPYLTOLUENE AND PRODUCTION AND USE THEREOF KUREHA CHEM IND CO LTD 1992-12-07 JP disclosed