Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.50 |
| ▸ | FABP4 | P15090 | 4/20 | 0.48 |
| ▸ | FABP3 | P05413 | 2/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19622450 | 0.85 | CA1 (0.44) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL9618707 | 0.85 | GABRA1 (0.43) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL22525916 | 0.80 | GABRA1 (0.64) | GABRA1GABRB2GABRB1LMNAALDH1A1 | |
| SCHEMBL17935190 | 0.80 | CA1 (0.55) | GABRA1GABRB2FABP4FABP3GABRB1 | |
| SCHEMBL26203737 | 0.78 | GABRA1 (0.42) | GABRA1GABRB2GABRB1LMNACA1 | |
| SCHEMBL26203728 | 0.76 | GABRA1 (0.41) | GABRA1GABRB2GABRB1LMNACA1 | |
| SCHEMBL4714238 | 0.76 | GABRA1 (0.52) | GABRA1GABRB2GABRB1LMNACA1 | |
| SCHEMBL26218810 | 0.75 | GABRA1 (0.39) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL20285914 | 0.75 | GABRA1 (0.43) | GABRA1GABRB2FABP4FABP3FABP5 | |
| SCHEMBL9064395 | 0.74 | GABRA1 (0.52) | GABRA1GABRB2FABP4FABP3FABP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105273006-B | The preparation method of the tri isopropyl biphenyl of 2 dicyclohexylphosphontetrafluoroborate 2,4,6 | 盘锦格林凯默科技有限公司 | 2017-09-19 | — | — | CN | claimed |
| CN-105273006-A | Method for preparing 2-dicyclohexylphosphine-2,4,6-di-iso-propylbiphenyl | PANJIN GELIN KAIMO TECHNOLOGY CO LTD | 2016-01-27 | — | — | CN | claimed |
| CN-104327106-A | Preparation method of high-sterically-hindered arylborate compound | SHENZHEN RES INST THE HONG KONG POLYTECHNIC UNIVERSITY | 2015-02-04 | — | — | CN | claimed |
| CN-116478350-A | Poly (isomonoolefin) copolymer and application thereof | 北京石油化工学院 | 2023-07-25 | — | — | CN | disclosed |
| CN-116425930-A | Poly (isomonoolefin) copolymer, initiator system and application | 北京石油化工学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-113912795-B | Polyisomonoolefin copolymer, preparation method thereof, initiator and application | 北京石油化工学院 | 2022-11-22 | — | — | CN | disclosed |
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | NodThera Limited (GB) | 2022-08-25 | — | — | US | disclosed |
| CN-113912795-A | Polyisomonoolefin copolymer, preparation method thereof, initiator and application | 北京石油化工学院 | 2022-01-11 | — | — | CN | disclosed |
| CN-111349114-A | Method for synthesizing 2-dicyclohexylphosphine-2 ', 4 ', 6 ' -triisopropylbiphenyl | 河南省科学院化学研究所有限公司 | 2020-06-30 | — | — | CN | disclosed |
| CN-104327106-B | The preparation method of high steric-hindrance amino aryl boric acid esters compound | 香港理工大学深圳研究院 | 2017-11-10 | — | — | CN | disclosed |
| CN-105273006-B | The preparation method of the tri isopropyl biphenyl of 2 dicyclohexylphosphontetrafluoroborate 2,4,6 | 盘锦格林凯默科技有限公司 | 2017-09-19 | — | — | CN | disclosed |
| CN-105273006-A | Method for preparing 2-dicyclohexylphosphine-2,4,6-di-iso-propylbiphenyl | PANJIN GELIN KAIMO TECHNOLOGY CO LTD | 2016-01-27 | — | — | CN | disclosed |
| EP-1804848-B1 | IMPLANTABLE DEVICES COMPRISING BIOLOGICALLY ABSORBABLE STAR POLYMERS AND METHODS FOR FABRICATING THE SAME | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-07-15 | — | — | EP | disclosed |
| CN-104327106-A | Preparation method of high-sterically-hindered arylborate compound | SHENZHEN RES INST THE HONG KONG POLYTECHNIC UNIVERSITY | 2015-02-04 | — | — | CN | disclosed |
| US-20060095122-A1 | Implantable devices comprising biologically absorbable star polymers and methods for fabricating the same | ADVANCED CARDIOVASCULAR SYSTEMS, INC. | 2006-05-04 | — | — | US | disclosed |
| WO-2006011000-A1 | NOVEL C6-SUBSTITUTED FURANOID SUGAR AMINO ACIDS AND IMPROVED PROCESS FOR PREPARING THE SAME | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2006-02-02 | — | — | WO | disclosed |
| US-20060014939-A1 | Novel C6-substituted furanoid sugar amino acids and improved process for preparing the same | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH | 2006-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220267300-A1 | SULFONAMIDE DERIVATIVES AND USES THEREOF | IL1B, IL1A, CASP1 | GABRA1 2195/4885GABRB2 2922/4885FABP4 3668/4885 |
| US-20060014939-A1 | Novel C6-substituted furanoid sugar amino acids and improved process for preparing the same | HRH3, FFAR3, SSTR3 | GABRA1 2975/4885GABRB2 3162/4885FABP4 1546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.