Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619935 | 0.84 | KDM4E (0.43) | PTPN1CTSSCTSKS1PR3AAK1 | |
| SCHEMBL10627562 | 0.78 | CTSS (0.43) | CTSSCTSKS1PR3AAK1GABRB1 | |
| SCHEMBL10875101 | 0.77 | CTSS (0.42) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL10631836 | 0.76 | PTGS2 (0.47) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL6472733 | 0.75 | TDP1 (0.44) | MEN1NPC1RAB9AKMT2AGABRA1 | |
| SCHEMBL10627574 | 0.74 | CTSS (0.40) | CTSSCTSKS1PR3AAK1GABRB1 | |
| SCHEMBL481566 | 0.74 | EGLN1 (0.40) | GABRB1GABRB2PPARAMEN1KMT2A | |
| SCHEMBL3022374 | 0.74 | HRH4 (0.41) | BCHEGABRB1GABRB2MEN1NPC1 | |
| SCHEMBL23414334 | 0.73 | CTSS (0.50) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL31230469 | 0.73 | GABRB1 (0.56) | PTPN1CTSSCTSKS1PR3GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326887-B1 | BETA-LACTAM ANTIBIOTICS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AND IN THERAPEUTIC AGENTS | BAYER AG (DE) | 1992-09-16 | — | — | EP | disclosed |
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4980348-A | HETEROANELLATED PHENYLGLYCINE-BETA-LACTAM ANTIBIOTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-12-25 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |