Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SCN4A | P35499 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | GRM8 | O00222 | 1/20 | 0.45 |
| ▸ | GRM6 | O15303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.44 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977488 | 0.88 | RAB9A (0.60) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 | |
| Hydrochloric Acid SCHEMBL9619911 | 0.87 | RAB9A (0.59) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 | |
| SCHEMBL2631638 | 0.84 | NPC1 (0.59) | NPC1RAB9ASMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL13533137 | 0.76 | RAB9A (0.75) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 | |
| SCHEMBL6985206 | 0.74 | NPC1 (0.68) | NPC1RAB9ASMN1; SMN2HSD17B10TDP1 | |
| SCHEMBL23059332 | 0.73 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 | |
| SCHEMBL11722738 | 0.73 | SMN1; SMN2 (0.57) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 | |
| SCHEMBL9619945 | 0.73 | CTSS (0.38) | NPC1RAB9ASMN1; SMN2SCN4APIK3CD | |
| SCHEMBL74053 | 0.72 | RAB9A (0.68) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 | |
| SCHEMBL21028914 | 0.71 | SMN1; SMN2 (0.54) | NPC1RAB9ASMN1; SMN2SCN4AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |