Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8977487 | 0.91 | RAB9A (0.49) | NPC1RAB9ASCN4ASMN1; SMN2LIPG | |
| SCHEMBL10627562 | 0.79 | CTSS (0.43) | CTSSCTSKNPC1RAB9AS1PR3 | |
| SCHEMBL10627574 | 0.77 | CTSS (0.40) | CTSSCTSKNPC1RAB9AS1PR3 | |
| Bromide SCHEMBL9620176 | 0.77 | CTSS (0.40) | CTSSCTSKS1PR3PIK3CAPIK3CD | |
| SCHEMBL8977464 | 0.77 | LCK (0.54) | NPC1RAB9ASMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL11121473 | 0.77 | CTSS (0.41) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL3375087 | 0.75 | CTSK (0.51) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL3375084 | 0.75 | CTSK (0.51) | CTSSCTSKS1PR3GABRB1GABRB2 | |
| SCHEMBL9364669 | 0.75 | IRAK4 (0.43) | CTSSCTSKNPC1RAB9AS1PR3 | |
| SCHEMBL9620010 | 0.75 | CTSS (0.43) | CTSSCTSKS1PR3ALDH1A1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33948-E | Bactericides, animal growth regulators | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-02 | — | — | US | disclosed |
| US-4748163-A | Novel β-lactam antibiotics | BAYER AKTIENGESELLSCHAFT (DE) | 1988-05-31 | — | — | US | disclosed |
| EP-0195947-A2 | Beta-lactam antibiotics, process for their preparation and their use as and in medicaments | BAYER AG (DE) | 1986-10-01 | — | — | EP | disclosed |