Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 3/20 | 0.31 |
| ▸ | TET3 | O43151 | 1/20 | 0.31 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.31 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.30 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.30 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.30 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9619987 | 0.83 | TET2 (0.33) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL9620070 | 0.68 | ALDH1A1 (0.34) | — | |
| SCHEMBL9619979 | 0.65 | TET2 (0.34) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL352316 | 0.60 | ALDH1A1 (0.42) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL8679044 | 0.59 | TSHR (0.42) | — | |
| SCHEMBL38654491 | 0.59 | ALDH1A1 (0.37) | — | |
| SCHEMBL4443797 | 0.58 | TET2 (0.54) | TET2TET3TET1GRIK1GRIK2 | |
| SCHEMBL17381411 | 0.58 | TDP1 (0.39) | — | |
| SCHEMBL1696448 | 0.57 | ALDH1A1 (0.43) | TET2 | |
| SCHEMBL6036744 | 0.57 | TSHR (0.53) | TET2TET3TET1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0347381-B1 | UNSATURATED BETA-KETOESTERACETALS AND THEIR APPLICATIONS | CIBA-GEIGY AG (CH) | 1992-02-12 | — | — | EP | disclosed |
| EP-0347381-A1 | Unsaturated beta-ketoesteracetals and their applications | CIBA-GEIGY AG (CH) | 1989-12-20 | — | — | EP | disclosed |