SCHEMBL9620143

SCHEMBL9620143

CCCOc1cc(NC(=O)OC(C(=O)OC)C(C)C)c(F)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
ALDH1A1 P00352 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
TSHR P16473 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
CASP3 P42574 2/20 0.36
EBP Q15125 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
DHODH Q02127 2/20 0.35
EGFR P00533 2/20 0.35
KDR P35968 2/20 0.35
ABCB1 P08183 1/20 0.35
PDE4D Q08499 1/20 0.35
PPOX P50336 1/20 0.35
RECQL P46063 2/20 0.34
MAPT P10636 1/20 0.34
HTT P42858 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9620164 0.81 ALDH1A1 (0.38) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9620110 0.80 GAA (0.41) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9836639 0.74 DHODH (0.39) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9836710 0.74 RECQL (0.38) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9427678 0.72 ALDH1A1 (0.52) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9836189 0.72 DHODH (0.39) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9836957 0.72 TSHR (0.39) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL9836355 0.71 ALDH1A1 (0.46) LMNAALDH1A1L3MBTL1TSHRNPSR1
SCHEMBL10408155 0.71 DHODH (0.51) LMNANPSR1DHODHPPOX
SCHEMBL8998111 0.71 MAOA (0.39) LMNAALDH1A1L3MBTL1TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed