SCHEMBL9620164

SCHEMBL9620164

CCOC(=O)C(OC(=O)Nc1cc(OC(=O)OC)c(Cl)cc1F)C(C)C

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
LMNA P02545 2/20 0.38
NPSR1 Q6W5P4 2/20 0.38
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PPOX P50336 2/20 0.37
CASP3 P42574 2/20 0.36
CUL4A Q13619 2/20 0.34
POLB P06746 1/20 0.33
DHODH Q02127 4/20 0.33
RAB9A P51151 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9620110 0.88 GAA (0.41) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL8083816 0.86 ALDH1A1 (0.46) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9407131 0.81 ALDH1A1 (0.48) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9620143 0.81 LMNA (0.42) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL8998061 0.80 ALDH1A1 (0.35) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL8998049 0.79 ALDH1A1 (0.34) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL8998044 0.79 ALDH1A1 (0.34) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL9407125 0.79 HPGD (0.42) ALDH1A1LMNANPSR1CUL4APOLB
SCHEMBL8088073 0.77 TSHR (0.40) ALDH1A1LMNANPSR1TSHRL3MBTL1
SCHEMBL8760807 0.76 POLB (0.43) ALDH1A1LMNANPSR1TSHRL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed