SCHEMBL9620110

SCHEMBL9620110

CCOC(=O)C(OC(=O)Nc1cc(OC(C)C)c(Cl)cc1F)C(C)C

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.41
MAPK1 P28482 1/20 0.41
PPOX P50336 2/20 0.40
P2RX3 P56373 1/20 0.39
RORC P51449 1/20 0.37
CASP3 P42574 2/20 0.37
DHODH Q02127 5/20 0.36
LMNA P02545 3/20 0.36
NPSR1 Q6W5P4 3/20 0.36
MEN1 O00255 2/20 0.36
MAPT P10636 2/20 0.36
KMT2A Q03164 2/20 0.36
ALDH1A1 P00352 2/20 0.36
TSHR P16473 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
KCNQ3 O43525 1/20 0.35
KCNQ2 O43526 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9620164 0.88 ALDH1A1 (0.38) PPOXCASP3DHODHLMNANPSR1
SCHEMBL10576902 0.87 P2RX3 (0.46) GAAMAPK1PPOXP2RX3RORC
SCHEMBL9620143 0.80 LMNA (0.42) PPOXCASP3DHODHLMNANPSR1
SCHEMBL27368859 0.78 RORC (0.40) GAAMAPK1PPOXRORCDHODH
SCHEMBL27314992 0.77 DHODH (0.37) GAAMAPK1RORCDHODHLMNA
SCHEMBL9835444 0.76 RORC (0.39) GAAMAPK1PPOXRORCDHODH
SCHEMBL9836594 0.76 RORC (0.47) GAAMAPK1PPOXRORCDHODH
SCHEMBL9836339 0.75 DHODH (0.40) GAAMAPK1RORCDHODHLMNA
SCHEMBL9836348 0.75 RORC (0.37) GAAMAPK1P2RX3RORCDHODH
SCHEMBL9836714 0.75 LMNA (0.41) GAAMAPK1P2RX3RORCDHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5100457-A OXAZOLIDINEDIONE COMPOUNDS, THE PROCESS FOR PREPARING THE SAME AND HERBICIDAL COMPOSITION CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1992-03-31 US disclosed
EP-0382884-A1 Oxazolidinedione compounds, the process for preparing the same and herbicidal composition containing the same SAGAMI CHEMICAL RESEARCH CENTER (JP) 1990-08-22 EP disclosed