Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1692164 | 0.83 | CA14 (0.39) | ALOX15ALDH1A1MGAMGAASI | |
| SCHEMBL10029422 | 0.83 | ALDH1A1 (0.39) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL10029421 | 0.82 | ALDH1A1 (0.42) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL10012514 | 0.80 | ALDH1A1 (0.40) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL10029423 | 0.80 | ALDH1A1 (0.40) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL28095310 | 0.75 | LMNA (0.36) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL28213322 | 0.75 | ALDH1A1 (0.36) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL15649073 | 0.74 | ALDH1A1 (0.48) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL1828667 | 0.74 | MMP8 (0.35) | ALOX15ALDH1A1LMNAHSD17B10MGAM | |
| SCHEMBL1578905 | 0.74 | MMP8 (0.35) | ALOX15ALDH1A1LMNAHSD17B10MGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0278732-B1 | FLUORINE-CONTAINING VITAMIN D2 DERIVATIVES | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5047564-A | Osteoporosis | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0278732-A1 | Fluorine-containing vitamin D2 derivatives | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1988-08-17 | — | — | EP | disclosed |