Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28213322 | 0.90 | ALDH1A1 (0.36) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL10012514 | 0.86 | ALDH1A1 (0.40) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL10029421 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL28095310 | 0.81 | LMNA (0.36) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL10029422 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL9620864 | 0.80 | ALOX15 (0.41) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL1828667 | 0.79 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL1578905 | 0.79 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL31054671 | 0.79 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 | |
| SCHEMBL1578908 | 0.79 | MMP8 (0.35) | ALDH1A1LMNAHSD17B10GAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569439-B2 | Hardener for silicone rubber materials | NITRO-CHEMIE ASCHAU GMBH (DE) | 2013-10-29 | — | — | US | disclosed |
| US-20120016072-A1 | HARDENER FOR SILICONE RUBBER MATERIALS | NITRO-CHEME ASCHAU GmbH (DE) | 2012-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016072-A1 | HARDENER FOR SILICONE RUBBER MATERIALS | HACD2, HACD3, ITGA2 | ALDH1A1 559/4885LMNA 2007/4885HSD17B10 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.