Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621523 | 1.00 | HPN (0.37) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL9735816 | 0.88 | HPN (0.39) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL9735957 | 0.81 | KDM4E (0.42) | — | |
| SCHEMBL646924 | 0.71 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL9621762 | 0.69 | HPN (0.37) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL13909737 | 0.69 | HMGCR (0.43) | — | |
| SCHEMBL8702044 | 0.68 | ALOX15 (0.59) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL8834366 | 0.68 | HPN (0.44) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL9550806 | 0.68 | MAPT (0.50) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL5692187 | 0.68 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162365-A | 5-lipoxygenase inhibitors | G. D. SEARLE & CO. (US) | 1992-11-10 | — | — | US | claimed |