Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621523 | 0.88 | HPN (0.37) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL9621054 | 0.88 | HPN (0.37) | HPNMAPTALOX15SIRT5 | |
| SCHEMBL9735957 | 0.79 | KDM4E (0.42) | KDM4EALDH1A1GAA | |
| SCHEMBL8530578 | 0.77 | ALOX15 (0.49) | HPNMAPTALOX15SIRT5KDM4E | |
| SCHEMBL9736493 | 0.71 | VCAM1 (0.37) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL9868145 | 0.71 | VCAM1 (0.36) | HPNMAPTALOX15SIRT5GAA | |
| SCHEMBL9847668 | 0.68 | HPN (0.39) | HPNMAPTALOX15SIRT5KDM4E | |
| SCHEMBL3406163 | 0.67 | — | — | |
| SCHEMBL646924 | 0.66 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5ALDH1A1 | |
| SCHEMBL5692187 | 0.66 | ALOX15 (0.63) | HPNMAPTALOX15SIRT5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093363-A | Antilipemic agents | SHIONOGI & CO., LTD. (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0414206-A2 | 2,4,6-Substituted phenol derivatives | SHIONOGI & CO., LTD. (JP) | 1991-02-27 | — | — | EP | disclosed |