SCHEMBL9621178

SCHEMBL9621178

CN(CCC(=O)O)CC(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PHF8 Q9UPP1 4/20 0.44
KDM2A Q9Y2K7 4/20 0.44
KDM7A Q6ZMT4 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
MVD P53602 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
EYA2 O00167 1/20 0.43
APP P05067 1/20 0.43
ACE P12821 1/20 0.43
BHMT Q93088 1/20 0.43
LMNA P02545 2/20 0.42
KDM4E B2RXH2 1/20 0.42
CHRM2 P08172 1/20 0.42
ADRA2A P08913 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
DRD1 P21728 1/20 0.42
SLC6A2 P23975 1/20 0.42
SLC6A4 P31645 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5342021 0.87 MVD (0.41) PHF8KDM2AKDM7AMEN1KMT2A
SCHEMBL918386 0.86 TDP1 (0.50) PHF8KDM2AMVDTDP1EYA2
SCHEMBL718216 0.86 KMT2A (0.56) PHF8KDM2AKDM7AMEN1KMT2A
SCHEMBL13464163 0.85 LMNA (0.46) PHF8KDM2AKDM7AMEN1KMT2A
SCHEMBL11239382 0.83 KMT2A (0.54) PHF8KDM2AKDM7AMEN1KMT2A
Methane SCHEMBL15776806 0.83 KMT2A (0.54) PHF8KDM2AKDM7AMEN1KMT2A
SCHEMBL8520631 0.81 TSHR (0.52) PHF8MEN1KMT2ATDP1APP
SCHEMBL26431474 0.81 PHF8 (0.43) PHF8KDM2AKDM7AMEN1KMT2A
SCHEMBL22815161 0.81 TDP1 (0.46) PHF8MVDTDP1EYA2APP
SCHEMBL11723098 0.81 LTA4H (0.49) PHF8MVDTDP1EYA2APP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160287731-A1 Compounds for Positron Emission Tomography ENDOCYTE, INC 2016-10-06 US disclosed
EP-0201340-B1 TONER COMPOSITION AND METHOD FOR PREPARING THE SAME Kao Corporation (JP) 1992-04-01 EP disclosed
US-4749638-A CARBON BLACK, DISPERSANT, POLYMERIC BINDER OIL PHASE EMULSION POLYMERIZATION KAO CORPORATION (JP) 1988-06-07 US disclosed
EP-0201340-A2 Toner composition and method for preparing the same Kao Corporation (JP) 1986-11-12 EP disclosed
US-4405705-A HYDROPHILIC TOYO BOSEKI KABUSHIKI KAISHA T/A TOYOBA CO., LTD. (JP) 1983-09-20 US disclosed
US-4220704-A Water soluble photosensitive resin compositions comprising a polyamide or its salt TOYOBO CO., LTD. (JP) 1980-09-02 US disclosed
US-4188221-A REACTION PRODUCT OF (METH)ACRYLIC ACID AND A POLYGLYCIDYL ETHER OF A POLYOL, MOISTURE RESISTANCE TOYO BOSEKI KABUSHIKI KAISHA (JP) 1980-02-12 US disclosed
US-4187112-A Photosensitive plate containing nitrogen containing condensation type polyesters TOYOBO CO., LTD. (JP) 1980-02-05 US disclosed
US-4145222-A Water soluble photosensitive resin composition comprising a polyamide or its ammonium salt TOYOBO CO., LTD. (JP) 1979-03-20 US disclosed
US-4096123-A COPOLYMER CONTAINING A TERTIARY AMINO GROUP TOYO BOSEKI KABUSHIKI KAISHA (JA) 1978-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287731-A1 Compounds for Positron Emission Tomography FOLH1, FOLR2, FOLR1 PHF8 2637/4885KDM2A 1519/4885KDM7A 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.