Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 5/20 | 0.41 |
| ▸ | PI4KB | Q9UBF8 | 5/20 | 0.41 |
| ▸ | PI4KA | P42356 | 4/20 | 0.41 |
| ▸ | PI4K2B | Q8TCG2 | 4/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.33 |
| ▸ | ADCY5 | O95622 | 2/20 | 0.33 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adenine SCHEMBL18321272 | 0.93 | GDA (0.43) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL385841 | 0.90 | PI4KA (0.45) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL3414603 | 0.90 | PI4KA (0.48) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL8110 | 0.90 | PI4KA (0.48) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL3416954 | 0.90 | PI4KA (0.48) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL3413247 | 0.90 | PI4KA (0.48) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL28763031 | 0.89 | PI4KA (0.39) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL14125907 | 0.89 | PI4KA (0.39) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL1871837 | 0.88 | PI4KA (0.44) | GDAPI4K2API4KBPI4KAPI4K2B | |
| Adenine SCHEMBL10868999 | 0.88 | PI4KA (0.47) | GDAPI4K2API4KBPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186454-B1 | 6-PURINYL N-(2-CHLOROETHYL) CARBAMATE AND THIOCARBAMATE, A PROCESS FOR THEIR PREPARATION AND USE THEREOF | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1992-04-08 | — | — | EP | disclosed |
| US-4720497-A | 6-purinyl N-/2-chloroethyl/carbamate and thiocarbamate and process for the preparation thereof | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1988-01-19 | — | — | US | disclosed |
| EP-0186454-A2 | 6-Purinyl N-(2-chloroethyl) carbamate and thiocarbamate, a process for their preparation and use thereof | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1986-07-02 | — | — | EP | disclosed |