SCHEMBL3784795

SCHEMBL3784795

O=Cc1cccc(Cl)c1C=O

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 4/20 0.73
ALDH1A1 P00352 4/20 0.73
MEN1 O00255 3/20 0.73
KMT2A Q03164 3/20 0.73
LMNA P02545 2/20 0.48
THRB P10828 1/20 0.48
BLM P54132 1/20 0.48
ERN1 O75460 2/20 0.41
HSP90AA1 P07900 1/20 0.41
TSHR P16473 1/20 0.39
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
NPC1 O15118 1/20 0.38
POLB P06746 1/20 0.38
MAPT P10636 1/20 0.38
RAB9A P51151 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HDAC1 Q13547 1/20 0.37
HDAC8 Q9BY41 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28568606 0.98 TDP1 (0.70) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL96214 0.85 ALDH1A1 (1.00) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL8743000 0.82 KMT2A (0.50) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL28806185 0.82 ALDH1A1 (0.94) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL547829 0.82 KMT2A (0.61) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL14877176 0.78 ALDH1A1 (0.54) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL95211 0.78 ALDH1A1 (0.54) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL30011286 0.78 ALDH1A1 (0.54) TDP1ALDH1A1MEN1KMT2ALMNA
SCHEMBL97422 0.77
SCHEMBL29815450 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105111426-B Quaternary ammonium salt functionalized porphyrin catalyst and preparation method thereof 武汉理工大学 2017-05-17 CN disclosed
CN-105111426-A Quaternary ammonium salt functionalized porphyrin catalyst and preparation method thereof UNIV WUHAN TECH 2015-12-02 CN disclosed
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-04-08 US disclosed
EP-1914221-A1 PROCESS FOR PRODUCING BIARYL COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-04-23 EP disclosed
EP-0863921-A1 POLYVINYL ACETAL COPOLYMERS AND THEIR PREPARATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1998-09-16 EP disclosed
WO-1997019961-A1 POLYVINYL ACETAL COPOLYMERS AND THEIR PREPARATION E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-06-05 WO disclosed
EP-0481788-B1 Process for preparing ink jet recording head CANON KK (JP) 1997-01-02 EP disclosed
EP-0530591-B1 Vinyl alcohol unit-containing polymer fibers having high moisture absorption and high water absorption and process for producing same KURARAY CO (JP) 1995-05-10 EP disclosed
EP-0613719-A1 Nickel catalyst for the cyanation of aromatic halides DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1994-09-07 EP disclosed
EP-0613720-A1 Nickel catalyst for the cyanation of aromatic halides DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1994-09-07 EP disclosed
US-5334999-A Device for preparing ink jet recording head with channels containing energy generating elements CANON KABUSHIKI KAISHA (JP) 1994-08-02 US disclosed
US-5304420-A Vinyl alcohol unit-containing polymer fibers having high moisture absorption and high water absorption KURARAY CO., LTD. (JP) 1994-04-19 US disclosed
EP-0530591-A1 Vinyl alcohol unit-containing polymer fibers having high moisture absorption and high water absorption and process for producing same Kuraray Co., Ltd. (JP) 1993-03-10 EP disclosed
EP-0481788-A1 Process for preparing ink jet recording head CANON KABUSHIKI KAISHA (JP) 1992-04-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087680-A1 METHOD FOR PRODUCING BIARYL COMPOUND NISCH, BLVRB, BBOX1 TDP1 4196/4885ALDH1A1 4339/4885MEN1 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.