Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | TERT | O14746 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | TRPM5 | Q9NZQ8 | 2/20 | 0.37 |
| ▸ | PTGFR | P43088 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621744 | 0.80 | MTNR1A (0.40) | MAOATERTLMNATRPM5PTGFR | |
| SCHEMBL9621743 | 0.80 | MTNR1A (0.40) | MAOATERTLMNATRPM5PTGFR | |
| SCHEMBL9621740 | 0.80 | MTNR1A (0.40) | MAOATERTLMNATRPM5PTGFR | |
| SCHEMBL6200206 | 0.79 | MAOA (0.57) | MAOAMAOBSLC6A4MTNR1AMTNR1B | |
| SCHEMBL4392690 | 0.73 | GRM5 (0.40) | MAOAGRM5LMNAPNMTPOLB | |
| SCHEMBL29993511 | 0.73 | GRM5 (0.47) | MAOAGRM5PNMTMAOBPOLB | |
| SCHEMBL711648 | 0.73 | GRM5 (0.47) | MAOAGRM5PNMTMAOBPOLB | |
| SCHEMBL5543812 | 0.71 | MAOB (0.40) | MAOATERTGRM5LMNAMAOB | |
| SCHEMBL27864550 | 0.71 | PNMT (0.62) | CHRM2CHRM1CHRM3PNMTMAPT | |
| SCHEMBL7867405 | 0.71 | EPHX1 (0.40) | MAOAGRM5LMNAMAOBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0323915-B1 | BETA-HYDROXYKETONE AND ITS PRODUCTION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-08 | — | — | EP | disclosed |
| US-5101076-A | β-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-31 | — | — | US | disclosed |
| US-5041679-A | Beta-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-08-20 | — | — | US | disclosed |
| EP-0323915-A1 | Beta-hydroxyketone and its production | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-07-12 | — | — | EP | disclosed |