Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K7 | O43318 | 1/20 | 0.35 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9621465 | 0.80 | PDPK1 (0.47) | DRD3 | |
| SCHEMBL29775862 | 0.76 | PARP1 (0.36) | MAP3K7TAB1 | |
| SCHEMBL2314712 | 0.76 | PARP1 (0.33) | MAP3K7TAB1 | |
| SCHEMBL2938606 | 0.75 | MAP3K7 (0.37) | MAP3K7TAB1 | |
| SCHEMBL9621609 | 0.73 | NOTUM (0.36) | ADORA3ADORA2B | |
| SCHEMBL20322822 | 0.71 | NOTUM (0.39) | MAP3K7TAB1 | |
| SCHEMBL2938155 | 0.69 | BRD4 (0.40) | — | |
| SCHEMBL14347083 | 0.67 | PDPK1 (0.37) | MAP3K7TAB1 | |
| SCHEMBL2940695 | 0.67 | PDPK1 (0.36) | DRD3 | |
| SCHEMBL30688741 | 0.67 | L3MBTL1 (0.45) | MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0186454-B1 | 6-PURINYL N-(2-CHLOROETHYL) CARBAMATE AND THIOCARBAMATE, A PROCESS FOR THEIR PREPARATION AND USE THEREOF | SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu (CS) | 1992-04-08 | — | — | EP | claimed |
| US-4720497-A | 6-purinyl N-/2-chloroethyl/carbamate and thiocarbamate and process for the preparation thereof | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1988-01-19 | — | — | US | claimed |
| JP-61186382-A | — | — | None | — | — | JP | disclosed |
| US-4720497-A | 6-purinyl N-/2-chloroethyl/carbamate and thiocarbamate and process for the preparation thereof | SPOFA, SPOJENE PODNIKY PRO ZDRAVOTNICKOU VYROBU (CS) | 1988-01-19 | — | — | US | disclosed |
| JP-S61186382-A | 6-PURINYL N-(2-CHLOROETHYL)CARBAMATE AND THIOCARBAMATE AND MANUFACTURE | SPOFA VEREINIGTE PHARMA WERKE | 1986-08-20 | — | — | JP | disclosed |