Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 10/20 | 0.61 |
| ▸ | RARG | P13631 | 10/20 | 0.61 |
| ▸ | RARA | P10276 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | PGR | P06401 | 1/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.61 |
| ▸ | GOT1 | P17174 | 1/20 | 0.61 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622121 | 0.92 | ALDH1A1 (0.53) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL9622143 | 0.87 | RARB (0.48) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL6878528 | 0.84 | KMT2A (0.51) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL9300831 | 0.83 | RARB (0.69) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL6364826 | 0.81 | RARB (0.70) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL8458512 | 0.81 | RARB (0.81) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL5081241 | 0.81 | RARG (0.72) | RARBRARGRARAKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL9079139 | 0.80 | RARG (0.71) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL7904172 | 0.79 | KMT2A (0.48) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL8766318 | 0.77 | RARG (0.77) | RARBRARGRARAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | claimed |
| US-5093516-A | AROMATIC COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND THEIR USE IN HUMAN AND VETERINARY MEDICINE AND FOR COSMETIC COMPOSITIONS | L'OREAL (FR) | 1992-03-03 | — | — | US | disclosed |
| US-5023363-A | Antiinflammatory agent, antiallergens, skin disorders, vision defects | L'OREAL (FR) | 1991-06-11 | — | — | US | disclosed |