Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 12/20 | 0.69 |
| ▸ | RARG | P13631 | 12/20 | 0.69 |
| ▸ | RARA | P10276 | 9/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 1/20 | 0.69 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.69 |
| ▸ | GOT1 | P17174 | 1/20 | 0.69 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7902117 | 0.85 | RARG (0.69) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL9331667 | 0.85 | RARB (0.56) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL9622135 | 0.83 | RARB (0.61) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL10675397 | 0.82 | RARB (0.53) | RARBRARGRARAKMT2AMEN1 | |
| SCHEMBL3322256 | 0.82 | KMT2A (0.48) | RARBRARGRARAKMT2AMEN1 | |
| Adapalene SCHEMBL29357372 | 0.82 | RARB (1.00) | RARBRARGRARAKMT2AMEN1 | |
| Adapalene SCHEMBL29393098 | 0.82 | RARB (1.00) | RARBRARGRARAKMT2AMEN1 | |
| Adapalene SCHEMBL2747 | 0.82 | RARB (1.00) | RARBRARGRARAKMT2AMEN1 | |
| Adapalene SCHEMBL4302240 | 0.82 | RARB (1.00) | RARBRARGRARAKMT2AMEN1 | |
| Adapalene SCHEMBL29688458 | 0.82 | RARB (1.00) | RARBRARGRARAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9616011-B2 | Personal care compositions | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160081902-A1 | PERSONAL CARE COMPOSITIONS | OSBORNE ROSEMARIE (US) | 2016-03-24 | — | — | US | disclosed |
| US-5292512-A | Cosmetic or pharmaceutical composition containing microspheres of polymers or of fatty substances filled with at least one active product | CENTRE INTERNATIONALE DE RECHERCHES DERMATOLOGIQUES (C.I.R.D.) (FR) | 1994-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160081902-A1 | PERSONAL CARE COMPOSITIONS | KRT18, CUTA, TTR | RARB 870/4885RARG 674/4885RARA 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.