Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GMNN | O75496 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 6/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6465332 | 0.98 | MAPT (0.58) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL14998165 | 0.98 | MAPT (0.58) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL28437029 | 0.98 | MAPT (0.58) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL15457916 | 0.98 | MAPT (0.58) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL8756244 | 0.95 | ALDH1A1 (0.59) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL18737489 | 0.91 | SMN1; SMN2 (0.57) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL9622162 | 0.87 | MAPT (0.53) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL18737683 | 0.85 | HDAC3 (0.50) | ALDH1A1MAPTGMNNTP53POLB | |
| SCHEMBL17399693 | 0.83 | HSD17B3 (0.63) | MAPTGMNNTP53POLBTHRB | |
| SCHEMBL3357504 | 0.83 | L3MBTL1 (0.55) | MAPTGMNNTP53POLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7385087-B2 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-10 | — | — | US | claimed |
| CN-100345824-C | Preparation method of alpha- (3-arylthio) acetophenone | BASF AG (DE) | 2007-10-31 | — | — | CN | claimed |
| EP-1678127-B1 | METHOD FOR THE PRODUCTION OF ALPHA-(3-ARYLTHIO)-ACETOPHENONES | BASF AG (DE) | 2007-07-25 | — | — | EP | claimed |
| US-20070060776-A1 | Method for the production of alpha-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-15 | — | — | US | claimed |
| EP-1603868-B1 | METHOD FOR PRODUCING ALPHA-(3-ARYLTHIO)-ACETOPHENONES | BASF AG (DE) | 2006-09-13 | — | — | EP | claimed |
| US-20060178537-A1 | Method for producing a-(3-arylthio)-acetophenones | BASF AKTIENGESELLSCHAFT (DE) | 2006-08-10 | — | — | US | claimed |
| EP-1678127-A1 | METHOD FOR THE PRODUCTION OF ALPHA-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-12 | — | — | EP | claimed |
| CN-1756738-A | Method for producing a-(3-arylthio)-acetophenones | BASF AG (DE) | 2006-04-05 | — | — | CN | claimed |
| EP-1603868-A1 | METHOD FOR PRODUCING a-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | claimed |
| WO-2005042477-A1 | METHOD FOR THE PRODUCTION OF $G(A)-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | claimed |
| WO-2004078705-A1 | METHOD FOR PRODUCING α-(3-ARYLTHIO)-ACETOPHENONES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-16 | — | — | WO | claimed |
| US-20230013624-A1 | RESIST COMPOSITION AND PATTERN FORMING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2023-01-19 | — | — | US | disclosed |
| US-9790199-B1 | Sulfoxide compound and method of producing benzothiophene derivatives using the same | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2017-10-17 | — | — | US | disclosed |
| US-9766547-B2 | Pattern forming method, actinic ray-sensitive or radiation-sensitive resin composition, resist film, method of manufacturing electronic device using the same, and electronic device | FUJIFILM CORPORATION (JP) | 2017-09-19 | — | — | US | disclosed |
| US-9751852-B1 | Sulfoxide compound and method of producing benzothiophene derivatives using the same | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2017-09-05 | — | — | US | disclosed |
| WO-1997034888-A1 | SYNTHESIS OF 3-[4-(2-AMINOETHOXY)-BENZOYL]-2-ARYL-6-HYDROXY-BENZO[b]THIOPHENES | ELI LILLY AND COMPANY (US) | 1997-09-25 | — | — | WO | disclosed |
| US-5629425-A | NONSTEROIDAL ANTIESTROGEN | ELI LILLY AND COMPANY (US) | 1997-05-13 | — | — | US | disclosed |
| WO-1997004361-A1 | HETEROGENEOUS PHOTO-INITIATORS, PHOTOPOLYMERISABLE COMPOSITIONS AND THEIR USE | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1997-02-06 | — | — | WO | disclosed |
| US-4185110-A | ANTIALLERGENS | CIBA-GEIGY CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |
| US-4055652-A | 1-[β(R-thio)phenethyl]imidazoles and derivatives thereof | SYNTEX (U.S.A.) INC. (US) | 1977-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060776-A1 | Method for the production of alpha-(3-arylthio)-acetophenones | CBR3, CYB5R3, ME3 | ALDH1A1 764/4885MAPT 4368/4885GMNN 3147/4885 |
| US-20060178537-A1 | Method for producing a-(3-arylthio)-acetophenones | ARSA, TST, SULT1A1 | ALDH1A1 74/4885MAPT 4195/4885GMNN 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.