Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 16/20 | 0.57 |
| ▸ | DRD2 | P14416 | 9/20 | 0.57 |
| ▸ | HTR1A | P08908 | 8/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622852 | 0.88 | HTR2B (0.45) | HTR2BDRD2HTR1A | |
| SCHEMBL9622931 | 0.81 | HCRTR1 (0.44) | HTR2BDRD2 | |
| SCHEMBL9622201 | 0.79 | MEN1 (0.42) | BCHEACHE | |
| SCHEMBL9622928 | 0.78 | MEN1 (0.42) | BCHEACHE | |
| SCHEMBL9622848 | 0.74 | CHRM2 (0.45) | HTR2BDRD2 | |
| SCHEMBL9622857 | 0.72 | LMNA (0.42) | HTR2BDRD2 | |
| SCHEMBL9367280 | 0.72 | SMN1; SMN2 (0.48) | HTR2B | |
| SCHEMBL9367286 | 0.72 | SMN1; SMN2 (0.48) | HTR2B | |
| SCHEMBL9366603 | 0.72 | CPT1B (0.55) | — | |
| SCHEMBL13499610 | 0.71 | HTR2B (0.65) | HTR2BDRD2HTR1AACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |