Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 9/20 | 0.45 |
| ▸ | DRD2 | P14416 | 7/20 | 0.45 |
| ▸ | HTR1A | P08908 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622197 | 0.88 | HTR2B (0.57) | HTR2BDRD2HTR1A | |
| SCHEMBL9622857 | 0.81 | LMNA (0.42) | HTR2BDRD2LMNASMN1; SMN2SLC6A3 | |
| SCHEMBL9622931 | 0.73 | HCRTR1 (0.44) | HTR2BDRD2LMNASLC6A3CHRM2 | |
| SCHEMBL9622599 | 0.72 | LMNA (0.44) | HTR2BDRD2LMNASMN1; SMN2SLC6A3 | |
| SCHEMBL9622597 | 0.72 | LMNA (0.44) | HTR2BDRD2LMNASMN1; SMN2SLC6A3 | |
| SCHEMBL9622848 | 0.72 | CHRM2 (0.45) | HTR2BDRD2LMNASMN1; SMN2SLC6A3 | |
| SCHEMBL9622201 | 0.71 | MEN1 (0.42) | LMNASMN1; SMN2CHRM2OPRK1HTT | |
| SCHEMBL9622928 | 0.70 | MEN1 (0.42) | LMNASMN1; SMN2CHRM2OPRK1HTT | |
| SCHEMBL9366603 | 0.70 | CPT1B (0.55) | LMNACHRM2OPRK1HTTMEN1 | |
| SCHEMBL9367286 | 0.66 | SMN1; SMN2 (0.48) | HTR2BLMNASMN1; SMN2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |