Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9622201 | 0.82 | MEN1 (0.42) | MEN1KMT2AKDM4ECYP1A2CHRM2 | |
| SCHEMBL9622931 | 0.80 | HCRTR1 (0.44) | MEN1KMT2AKDM4ECYP1A2CHRM2 | |
| SCHEMBL9622197 | 0.78 | HTR2B (0.57) | BCHEACHE | |
| SCHEMBL9622848 | 0.75 | CHRM2 (0.45) | MEN1KMT2AKDM4ECYP1A2CHRM2 | |
| SCHEMBL9367286 | 0.73 | SMN1; SMN2 (0.48) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL9367280 | 0.73 | SMN1; SMN2 (0.48) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 | |
| SCHEMBL9622857 | 0.71 | LMNA (0.42) | MEN1KMT2AKDM4ECYP1A2CHRM2 | |
| SCHEMBL9366603 | 0.71 | CPT1B (0.55) | MEN1KMT2AKDM4ECYP1A2CHRM2 | |
| SCHEMBL9622852 | 0.70 | HTR2B (0.45) | MEN1KMT2AKDM4ECYP1A2CHRM2 | |
| SCHEMBL9623023 | 0.69 | KDM4E (0.49) | MEN1KMT2AKDM4ECYP1A2CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |