Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9367280 | 1.00 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| Fumaric Acid SCHEMBL9622181 | 0.93 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| Fumaric Acid SCHEMBL9622178 | 0.93 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| Fumaric Acid SCHEMBL9622176 | 0.93 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL9622597 | 0.90 | LMNA (0.44) | SMN1; SMN2ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL9622599 | 0.90 | LMNA (0.44) | SMN1; SMN2ALDH1A1TSHRLMNAMAPT | |
| SCHEMBL9622905 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL9622908 | 0.86 | SMN1; SMN2 (0.49) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL9622236 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1GAATSHRLMNA | |
| SCHEMBL9622231 | 0.84 | SMN1; SMN2 (0.56) | SMN1; SMN2ALDH1A1GAATSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433167-B1 | Piperidine derivates, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 1994-03-02 | — | — | EP | claimed |
| JP-6340626-A | — | — | None | — | — | JP | disclosed |
| JP-H06340626-A | NEW PIPERIDINE COMPOUND, ITS PREPARATION AND ITS PHARMACEUTICAL COMPOSITION | ADIR | 1994-12-13 | — | — | JP | disclosed |
| US-5126356-A | Antiischemic agents | ADIR ET COMPAGNIE (FR) | 1992-06-30 | — | — | US | disclosed |