Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 14/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 13/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | PRKCB | P05771 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 1/20 | 0.44 |
| ▸ | PRKCA | P17252 | 1/20 | 0.44 |
| ▸ | PRKCH | P24723 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.44 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.44 |
| ▸ | MYLK | Q15746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377476 | 0.89 | CHEK1 (0.50) | WEE1CHEK1CDK4PRKCAMYLK | |
| SCHEMBL9623107 | 0.86 | MYLK (0.46) | WEE1CHEK1SRCMYLKROCK2 | |
| SCHEMBL29351301 | 0.86 | MYLK (0.46) | WEE1CHEK1SRCMYLKROCK2 | |
| SCHEMBL9623259 | 0.85 | CHEK1 (0.43) | WEE1CHEK1SRCPRKCAMYLK | |
| Hydrochloric Acid SCHEMBL9623312 | 0.85 | MYLK (0.45) | WEE1CHEK1SRCMYLKROCK2 | |
| SCHEMBL9623136 | 0.85 | MYLK (0.45) | WEE1CHEK1SRCMYLKROCK2 | |
| SCHEMBL9622994 | 0.83 | ROCK2 (0.45) | WEE1CHEK1MYLKROCK2 | |
| SCHEMBL9622489 | 0.83 | MYLK (0.45) | WEE1CHEK1SRCPRKCAMYLK | |
| SCHEMBL9623315 | 0.82 | MYLK (0.45) | WEE1CHEK1SRCPRKCAPRKCQ | |
| SCHEMBL9623320 | 0.82 | CHEK1 (0.44) | WEE1CHEK1SRCPRKCAMYLK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166204-A | ISOINDOLE DERIVATIVES AND SALTS THEREOF AND ANTITUMOR AGENT COMPRISING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 1992-11-24 | — | — | US | claimed |