SCHEMBL9623098

SCHEMBL9623098

CCCCC(C#N)=Cc1ccc(O)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.50
MEN1 O00255 4/20 0.50
CISD1 Q9NZ45 2/20 0.50
THRB P10828 1/20 0.50
MIF P14174 1/20 0.47
ESR1 P03372 4/20 0.46
ESR2 Q92731 4/20 0.46
ALDH1A1 P00352 6/20 0.45
HPGD P15428 3/20 0.45
CYP3A4 P08684 2/20 0.45
EGFR P00533 1/20 0.45
CYP1A2 P05177 1/20 0.45
PKM P14618 1/20 0.45
TSHR P16473 1/20 0.45
MAPK1 P28482 1/20 0.45
BLM P54132 1/20 0.45
PMP22 Q01453 1/20 0.45
HIF1A Q16665 1/20 0.45
HSD17B10 Q99714 1/20 0.45
KDM4E B2RXH2 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20143067 0.85 LMNA (0.49) KMT2AMEN1ALDH1A1PKMTSHR
SCHEMBL14616300 0.82 KMT2A (0.57) KMT2AMEN1CISD1THRBESR1
SCHEMBL28752642 0.80 LMNA (0.55) KMT2AMEN1ALDH1A1EGFRPKM
SCHEMBL30481108 0.80 LMNA (0.55) KMT2AMEN1ALDH1A1EGFRPKM
SCHEMBL28752643 0.79 TDP1 (0.56) ALDH1A1EGFRLMNAPOLB
SCHEMBL11863725 0.74 MEN1 (0.59) KMT2AMEN1CISD1ALDH1A1HPGD
SCHEMBL28645928 0.74 MCL1 (0.47) KMT2AMEN1ALDH1A1HPGDPKM
SCHEMBL11853779 0.73 ALDH1A1 (0.50) KMT2AMEN1CISD1THRBESR1
SCHEMBL11858718 0.72 ALDH1A1 (0.60) KMT2AMEN1CISD1THRBESR1
SCHEMBL4601182 0.70 HSD17B3 (0.49) KMT2AMIFESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0119051-B2 A METHOD OF COATING A SUBSTRATE, A COATING COMPOSITION AND A COATED ARTICLE BASF Corporation (US) 1992-03-04 EP disclosed
EP-0119051-B1 A METHOD OF COATING A SUBSTRATE, A COATING COMPOSITION AND A COATED ARTICLE BASF Corporation (US) 1988-07-27 EP disclosed
EP-0139513-B1 FLEXIBLE COATING COMPOSITIONS FORD MOTOR COMPANY LIMITED (GB) 1988-06-01 EP disclosed
US-4720528-A Substrates with flexible coatings from epsilon-caprolactone modified acrylics BASF CORPORATION-INMONT DIVISION (US) 1988-01-19 US disclosed
EP-0138587-B1 FLEXIBLE BASECOAT/CLEARCOAT COATING COMPOSITIONS FORD MOTOR COMPANY LIMITED (GB) 1987-07-08 EP disclosed
US-4588787-A HYDROXY-CONTAINING URETHANE MODIFIED POLYESTER, WEATHER RESISTANT FORD MOTOR COMPANY (US) 1986-05-13 US disclosed
US-4546046-A Substrates with flexible coatings from epsilon-caprolactone modified acrylics GLASURIT AMERICA, INC. (US) 1985-10-08 US disclosed
US-4524192-A CROSSLINK POLYESTERURETHANE WITH AMINE-ALDEHYDE E. I. DU PONT DE NEMOURS AND COMPANY 1985-06-18 US disclosed
EP-0139513-A1 Flexible coating compositions FORD MOTOR COMPANY LIMITED (GB) 1985-05-02 EP disclosed
WO-1985001695-A1 FLEXIBLE BASECOAT/CLEARCOAT COATING COMPOSITIONS FORD MOTOR COMPANY (US) 1985-04-25 WO disclosed
WO-1985001737-A1 FLEXIBLE UNI-BASECOAT/TWO COMPONENT CLEARCOAT COATING COMPOSITIONS FORD MOTOR COMPANY (US) 1985-04-25 WO disclosed
WO-1985001694-A1 FLEXIBLE COATING COMPOSITIONS FORD MOTOR COMPANY (US) 1985-04-25 WO disclosed
WO-1985001733-A1 FLEXIBLE TWO COMPONENT URETHANE COATING COMPOSITIONS FORD MOTOR COMPANY (US) 1985-04-25 WO disclosed
EP-0138587-A2 Flexible basecoat/clearcoat coating compositions FORD MOTOR COMPANY LIMITED (GB) 1985-04-24 EP disclosed
EP-0119051-A1 A method of coating a substrate, a coating composition and a coated article BASF Corporation (US) 1984-09-19 EP disclosed
EP-0033725-A1 CLEAR COAT/COLOR COAT FINISH CONTAINING AN ULTRAVIOLET LIGHT STABILIZER E.I. DU PONT DE NEMOURS AND COMPANY (US) 1981-08-19 EP disclosed
WO-1981000233-A1 CLEAR COAT/COLOR COAT FINISH CONTAINING AN ULTRAVIOLET LIGHT STABILIZER DU PONT 1981-02-05 WO disclosed
US-4208465-A ACRYLIC POLYMERS; WEATHERABLE ENAMELS FOR AUTOMOBILES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1980-06-17 US disclosed
US-3953398-A 3,5-DI-TERT-ALKYL-4-HYDROXYCINNAMIC ACID OR ESTER AS STABILIZER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-04-27 US disclosed