Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 5/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10187523 | 0.82 | MCL1 (0.50) | KMT2AMEN1ALDH1A1HPGDPKM | |
| SCHEMBL14604980 | 0.82 | MCL1 (0.50) | KMT2AMEN1ALDH1A1HPGDPKM | |
| SCHEMBL18192045 | 0.82 | MCL1 (0.50) | KMT2AMEN1ALDH1A1HPGDPKM | |
| SCHEMBL9623098 | 0.82 | KMT2A (0.50) | KMT2AMEN1CISD1THRBESR1 | |
| SCHEMBL15521648 | 0.78 | ALDH1A1 (0.48) | KMT2AMEN1ALDH1A1MAPK1KDM4E | |
| SCHEMBL8402113 | 0.76 | LTA4H (0.43) | KMT2AMEN1ALDH1A1HPGDCYP3A4 | |
| SCHEMBL11853779 | 0.75 | ALDH1A1 (0.50) | KMT2AMEN1CISD1THRBESR1 | |
| SCHEMBL13412691 | 0.74 | MEN1 (0.63) | KMT2AMEN1CISD1THRBESR1 | |
| SCHEMBL26552262 | 0.74 | MEN1 (0.63) | KMT2AMEN1CISD1THRBESR1 | |
| SCHEMBL11858718 | 0.73 | ALDH1A1 (0.60) | KMT2AMEN1CISD1THRBESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8785627-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2014-07-22 | — | — | US | disclosed |
| US-8501890-B2 | Copolymerizable methine and anthraquinone compounds and articles containing them | Abbott Medical Optics Inc. (US) | 2013-08-06 | — | — | US | disclosed |
| US-20130018159-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | Abbott Medical Optics Inc. (US) | 2013-01-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130018159-A1 | COPOLYMERIZABLE METHINE AND ANTHRAQUINONE COMPOUNDS AND ARTICLES CONTAINING THEM | CRY1, AAAS, CYBA | KMT2A 736/4885MEN1 31/4885CISD1 990/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.