Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 8/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.54 |
| ▸ | PGR | P06401 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 8/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.52 |
| ▸ | AR | P10275 | 3/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.51 |
| ▸ | SERPINA6 | P08185 | 6/20 | 0.51 |
| ▸ | BLM | P54132 | 4/20 | 0.51 |
| ▸ | PMP22 | Q01453 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9623248 | 0.91 | SHBG (0.54) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL24476209 | 0.85 | SHBG (0.64) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL24476232 | 0.85 | SHBG (0.64) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL9348134 | 0.81 | LMNA (0.62) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL9348129 | 0.81 | LMNA (0.62) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL9348215 | 0.81 | LMNA (0.62) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL3744063 | 0.77 | SHBG (0.68) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL3744059 | 0.77 | SHBG (0.68) | SHBGNR3C1PGRALDH1A1ADRA1A | |
| SCHEMBL9623709 | 0.77 | ESR1 (0.37) | ARESR1CYP19A1 | |
| SCHEMBL11319124 | 0.77 | SHBG (0.71) | SHBGNR3C1PGRALDH1A1ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268400-B1 | STEROIDAL 17ALPHA-SILYL ETHERS AND PROCESS TO CORTICOIDS AND PROGESTERONES | THE UPJOHN COMPANY (US) | 1992-04-29 | — | — | EP | claimed |