Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 1/20 | 0.30 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.30 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624256 | 0.84 | NFE2L2 (0.46) | NFE2L2MEN1KMT2APDE4APDE4B | |
| SCHEMBL9623888 | 0.82 | RIPK1 (0.35) | RIPK1NFE2L2KDM4EMEN1ALDH1A1 | |
| SCHEMBL9624069 | 0.82 | MEN1 (0.36) | RIPK1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL2235524 | 0.78 | KIF11 (0.40) | RIPK1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL9624247 | 0.76 | KIF11 (0.31) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9857514 | 0.76 | HPGD (0.38) | RIPK1KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL10713999 | 0.72 | PDE4A (0.32) | NFE2L2KDM4EMEN1ALDH1A1HPGD | |
| SCHEMBL2154097 | 0.72 | KIF11 (0.38) | KDM4EMEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL9624228 | 0.69 | HSD11B1 (0.40) | KDM4EMEN1ALDH1A1KMT2A | |
| SCHEMBL2155172 | 0.69 | KIF11 (0.38) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307026-B1 | PROCESS FOR THE PREPARATION OF A BUTENE | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1992-03-18 | — | — | EP | disclosed |
| EP-0282142-B1 | PROCESS FOR THE CARBONYLATION OF OLEFINICALLY UNSATURATED COMPOUNDS WITH A PALLADIUM CATALYST | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-11 | — | — | EP | disclosed |
| EP-0307026-A1 | Process for the preparation of a butene | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1989-03-15 | — | — | EP | disclosed |
| US-4786443-A | Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst | SHELL OIL COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282142-A1 | Process for the carbonylation of olefinically unsaturated compounds with a palladium catalyst | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-09-14 | — | — | EP | disclosed |