Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL207512 | 0.69 | CYP2A6 (0.35) | — | |
| SCHEMBL9624198 | 0.69 | ALDH1A1 (0.35) | ALDH1A1RECQLHSD17B10 | |
| SCHEMBL9625629 | 0.69 | ALDH1A1 (0.37) | APPALDH1A1RECQLHSD17B10 | |
| SCHEMBL9624098 | 0.69 | NOX1 (0.31) | — | |
| SCHEMBL9625533 | 0.66 | TERT (0.41) | ALDH1A1RECQLHSD17B10 | |
| SCHEMBL16289709 | 0.65 | ALDH1A1 (0.37) | ALDH1A1 | |
| SCHEMBL5538925 | 0.65 | EPHX2 (0.39) | ALDH1A1HSD17B10 | |
| SCHEMBL4187399 | 0.64 | APP (0.38) | APPALDH1A1 | |
| SCHEMBL16288692 | 0.63 | — | — | |
| SCHEMBL616687 | 0.61 | IRAK4 (0.51) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |