Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | USP8 | P40818 | 1/20 | 0.38 |
| ▸ | USP7 | Q93009 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9624782 | 0.83 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL9624832 | 0.78 | KDM4E (0.65) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL4368104 | 0.76 | KDM4E (0.66) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL3278153 | 0.71 | ALDH1A1 (0.60) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL3782828 | 0.66 | ALDH1A1 (1.00) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL4367705 | 0.66 | ALDH1A1 (0.60) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL4369233 | 0.65 | ALDH1A1 (0.52) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL12253692 | 0.65 | RAB9A (0.76) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL4230408 | 0.64 | ALDH1A1 (0.48) | KDM4EHSD17B10ALDH1A1POLBRAB9A | |
| SCHEMBL4365496 | 0.64 | ALDH1A1 (0.48) | KDM4EHSD17B10ALDH1A1POLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116986-A | HETEROAROMATIC AMINE DERIVATIVES | DR. KARL THOMAE GMBH (DE) | 1992-05-26 | — | — | US | disclosed |
| US-4912115-A | Cardiovascular disorders | DR. KARL THOMAE GMBH (DE) | 1990-03-27 | — | — | US | disclosed |