Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11578901 | 0.84 | CA1 (0.53) | TRPA1MAPTMEN1KMT2ARAB9A | |
| SCHEMBL29181663 | 0.84 | SRC (0.67) | ALDH1A1TRPA1MAPTMEN1KMT2A | |
| SCHEMBL9625400 | 0.84 | SRC (0.67) | ALDH1A1TRPA1MAPTMEN1KMT2A | |
| SCHEMBL20710762 | 0.83 | CA1 (0.48) | MAPTMEN1KMT2ARAB9AL3MBTL1 | |
| SCHEMBL22321992 | 0.82 | L3MBTL1 (0.68) | ALDH1A1TRPA1MAPTMEN1KMT2A | |
| SCHEMBL10015247 | 0.82 | CYP3A4 (0.61) | TSHRCYP3A4MEN1KMT2APKM | |
| SCHEMBL10015245 | 0.82 | CYP3A4 (0.61) | TSHRCYP3A4MEN1KMT2APKM | |
| SCHEMBL131239 | 0.82 | CYP3A4 (0.61) | TSHRCYP3A4MEN1KMT2APKM | |
| SCHEMBL11662151 | 0.82 | TRPA1 (0.39) | ALDH1A1TRPA1MAPTMEN1KMT2A | |
| SCHEMBL22321994 | 0.80 | CA2 (0.58) | ALDH1A1TRPA1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0180327-B1 | ASSAY METHOD INVOLVING A PHASE SEPARATION, AND KIT THEREFOR | AMOCO CORPORATION (US) | 1990-04-18 | — | — | EP | claimed |
| US-4804625-A | MONITORING BY PHASE SEPARATION FOR BIOLOGICAL SUBSTANCES REACTED WITH AN ENZYME/SUBSTRATE SYSTEM TO FORM A DETECTABLE PRODUCT | AMOCO CORPORATION (US) | 1989-02-14 | — | — | US | claimed |
| EP-0180327-A1 | Assay method involving a phase separation, and kit therefor | AMOCO CORPORATION (US) | 1986-05-07 | — | — | EP | claimed |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS (US) | 2021-02-23 | — | — | US | disclosed |
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | THE BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER EDUCATION ON BEHALF OF THE UNIVERSITY OF NEVADA, LAS VEGAS | 2020-08-13 | — | — | US | disclosed |
| EP-0061731-B2 | NOVEL PHOSPHORIC ESTER AND A METHOD FOR QUANTITATIVE ANALYSIS OF AN ALKALINE PHOSPHATASE USING THE SAME AS A SUBSTRATE | Fuji Photo Film Co., Ltd. (JP) | 1992-01-29 | — | — | EP | disclosed |
| EP-0180327-B1 | ASSAY METHOD INVOLVING A PHASE SEPARATION, AND KIT THEREFOR | AMOCO CORPORATION (US) | 1990-04-18 | — | — | EP | disclosed |
| US-4804625-A | MONITORING BY PHASE SEPARATION FOR BIOLOGICAL SUBSTANCES REACTED WITH AN ENZYME/SUBSTRATE SYSTEM TO FORM A DETECTABLE PRODUCT | AMOCO CORPORATION (US) | 1989-02-14 | — | — | US | disclosed |
| EP-0061731-B1 | NOVEL PHOSPHORIC ESTER AND A METHOD FOR QUANTITATIVE ANALYSIS OF AN ALKALINE PHOSPHATASE USING THE SAME AS A SUBSTRATE | Fuji Photo Film Co., Ltd. (JP) | 1986-10-29 | — | — | EP | disclosed |
| EP-0180327-A1 | Assay method involving a phase separation, and kit therefor | AMOCO CORPORATION (US) | 1986-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200255461-A1 | METAL-FREE DIRECT ARYLATION OF DIALKYL PHOSPHONATES FOR THE SYNTHESIS OF MIXED ALKYL ARYL PHOSPHONATES | SLC35B2, PPIP5K2, PPA1 | ALDH1A1 4078/4885TSHR 733/4885CYP3A4 677/4885 |
| US-10927135-B2 | Metal-free direct arylation of dialkyl phosphonates for the synthesis of mixed alkyl aryl phosphonates | SLC35B2, PPIP5K2, PPA1 | ALDH1A1 4078/4885TSHR 733/4885CYP3A4 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.