Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | OGG1 | O15527 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909057 | 0.91 | CA12 (0.58) | MAPTKDM4ELMNAALDH1A1L3MBTL1 | |
| SCHEMBL17299368 | 0.85 | CA12 (0.50) | HIF1ABLMPMP22MAPTKDM4E | |
| SCHEMBL854839 | 0.85 | MAPT (0.63) | CYP3A4HIF1ABLMPMP22MAPT | |
| SCHEMBL3374385 | 0.85 | EPHX2 (0.56) | HIF1ABLMPMP22MAPTKDM4E | |
| SCHEMBL343630 | 0.83 | MPO (0.80) | MPOCYP3A4HIF1AKDM5ABLM | |
| SCHEMBL2678949 | 0.83 | MPO (0.80) | MPOCYP3A4HIF1AKDM5ABLM | |
| SCHEMBL92285 | 0.83 | GFER (0.59) | MPOCYP3A4HIF1AKDM5ABLM | |
| SCHEMBL13702393 | 0.83 | PLK1 (0.66) | MAPTLMNAALDH1A1CA1CA2 | |
| SCHEMBL17407652 | 0.83 | CA12 (0.51) | HIF1AMAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL12347956 | 0.83 | EPHX2 (0.54) | MAPTLMNAALDH1A1L3MBTL1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5094849-A | Antitumor | ELI LILLY AND COMPANY (US) | 1992-03-10 | — | — | US | claimed |