Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909057 | 0.89 | CA12 (0.58) | CA12CA9HDAC4HDAC6KMT2A | |
| SCHEMBL9625469 | 0.85 | MPO (0.59) | CA12CA9KMT2ALMNAMEN1 | |
| SCHEMBL2977016 | 0.84 | KDM4E (0.65) | EPHX2NR1H4KMT2ALMNAKDM4E | |
| SCHEMBL854839 | 0.83 | MAPT (0.63) | EPHX2CA12CA9HDAC4HDAC6 | |
| SCHEMBL17299368 | 0.83 | CA12 (0.50) | CA12CA9HDAC4HDAC6KMT2A | |
| SCHEMBL15168443 | 0.83 | LMNA (0.55) | EPHX2NR1H4HDAC4HDAC6KMT2A | |
| SCHEMBL26246561 | 0.82 | EPHX2 (0.54) | EPHX2NR1H4PARP10KMT2ALMNA | |
| SCHEMBL45720 | 0.81 | SMN1; SMN2 (0.57) | KMT2AMEN1SMN1; SMN2PARP1ALDH1A1 | |
| SCHEMBL2967223 | 0.81 | L3MBTL1 (0.63) | EPHX2KMT2AKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL92285 | 0.81 | GFER (0.59) | CA12CA9HDAC4HDAC6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8354444-B2 | Substituted pyrrolidine-2-carboxamides | HOFFMANN-LA ROCHE INC. (US) | 2013-01-15 | — | — | US | claimed |
| CN-102403478-A | Production method of high-permeability low-density lithium battery polyolefin diaphragm | TONGLING JINGNENG ELECTRONIC CO LTD | 2012-04-04 | — | — | CN | claimed |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-17 | — | — | US | claimed |
| EP-2188289-A2 | (7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-PIPERAZINES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATION | Lexicon Pharmaceuticals, Inc. (US) | 2010-05-26 | — | — | EP | claimed |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | DING QINGJIE | 2010-03-25 | — | — | US | claimed |
| WO-2009021169-A2 | (7H-PYRR0L0 [2, 3-D] PYRIMIDIN-4-YL) -PIPERAZINES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATION | LEXICON PHARMACEUTICALS, INC. (US) | 2009-02-12 | — | — | WO | claimed |
| CN-116768763-B | Preparation method and application of alicyclic carbamate | 中国科学院过程工程研究所 | 2026-02-27 | — | — | CN | disclosed |
| WO-2017136659-A2 | HUMANIZED ANTI-CD3 ANTIBODIES, CONJUGATES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017105985-A1 | PREPARATION OF ISOHEXIDE-3,6-DICARBALDEHYDES AND ISOHEXIDE-3,6-DIMETHANAMINES | ARCHER DANIELS MIDLAND COMPANY (US) | 2017-06-22 | — | — | WO | disclosed |
| EP-2534132-B1 | SUBSTITUTED PYRROLIDINE-2-CARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 2017-04-26 | — | — | EP | disclosed |
| EP-2188289-B1 | (7H-PYRROLO[2,3-D]PYRIMIDIN-4-YL)-PIPERAZINES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATION | LEXICON PHARMACEUTICALS INC (US) | 2015-10-28 | — | — | EP | disclosed |
| WO-2014153164-A1 | TARGETING AGENT ANTIBODY CONJUGATES AND USES THEREOF | THE CALIFORNIA INSTITUTE FOR BIOMEDICAL RESEARCH (US) | 2014-09-25 | — | — | WO | disclosed |
| EP-2597098-A1 | (7H-PYRROLO [2, 3-D] PYRIMIDIN-4-YL) -PIPERAZINES AS KINASE INHIBITORS FOR THE TREATMENT OF CANCER AND INFLAMMATION | Lexicon Pharmaceuticals, Inc. (US) | 2013-05-29 | — | — | EP | disclosed |
| CN-102403478-A | Production method of high-permeability low-density lithium battery polyolefin diaphragm | TONGLING JINGNENG ELECTRONIC CO LTD | 2012-04-04 | — | — | CN | disclosed |
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | F. HOFFMANN-LA ROCHE AG (CH) | 2010-06-17 | — | — | US | disclosed |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | DING QINGJIE | 2010-03-25 | — | — | US | disclosed |
| US-20080058525-A1 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | ZINK IMAGING, LLC | 2008-03-06 | — | — | US | disclosed |
| US-7282317-B2 | Dye complexes and use thereof in imaging members and methods | ZINK IMAGING, LLC (US) | 2007-10-16 | — | — | US | disclosed |
| EP-1200504-A2 | POLYMERISATION METHOD | Cambridge Display Technology Limited (GB) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001007502-A2 | POLYMERISATION METHOD | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152190-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | EPHX2 2619/4885NR1H4 3323/4885PARP10 74/4885 |
| US-20080058525-A1 | NOVEL DYE COMPLEXES AND USE THEREOF IN IMAGING MEMBERS AND METHODS | DBI, HSPE1, ABCB7 | EPHX2 2853/4885NR1H4 1342/4885PARP10 1567/4885 |
| US-20100075948-A1 | Substituted Pyrrolidine-2-Carboxamides | ARG2, CCNY, PYCR1 | EPHX2 2619/4885NR1H4 3323/4885PARP10 74/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.