Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 2/20 | 0.59 |
| ▸ | MPO | P05164 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | KDM5A | P29375 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.59 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.59 |
| ▸ | ESRRG | P62508 | 4/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | ESRRB | O95718 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5909057 | 0.91 | CA12 (0.58) | OPRM1OPRD1CA12CA9MAPT | |
| Chlorobenzene SCHEMBL27766061 | 0.86 | NPC1 (0.55) | GFEROPRM1OPRD1MAPTALDH1A1 | |
| SCHEMBL13445829 | 0.85 | GAA (0.53) | GFERMPOCYP3A4KDM5ABLM | |
| SCHEMBL27815909 | 0.85 | MAPT (0.50) | GFERMPOCYP3A4KDM5ABLM | |
| SCHEMBL166778 | 0.83 | KDM4E (0.62) | GFERMPOCYP3A4KDM5ABLM | |
| SCHEMBL8158111 | 0.83 | NR1H4 (0.54) | OPRM1OPRD1CA12CA9MAPT | |
| SCHEMBL12347956 | 0.83 | EPHX2 (0.54) | OPRM1OPRD1CA12CA9MAPT | |
| SCHEMBL17407652 | 0.83 | CA12 (0.51) | HIF1AOPRM1OPRD1CA12CA9 | |
| SCHEMBL9625469 | 0.83 | MPO (0.59) | GFERMPOCYP3A4KDM5ABLM | |
| SCHEMBL13702393 | 0.83 | PLK1 (0.66) | CA12CA9MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516672-A | CONTAINING A BENZENE DERIVATIVE AS STABILIZER; MEDICAL DIAGNOSIS; STORAGE STABILITY | KONICA CORPORATION (JP) | 1996-05-14 | — | — | US | claimed |
| EP-2922574-B1 | CHEMICALLY CLEAVABLE GROUP | TAGWORKS PHARMACEUTICALS B V (NL) | 2023-05-17 | — | — | EP | disclosed |
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. | 2023-04-27 | — | — | US | disclosed |
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| US-20200102264-A1 | MARMELIN ANALOGS AND METHODS OF USE IN CANCER TREATMENT | THE UNIVERSITY OF KANSAS (US) | 2020-04-02 | — | — | US | disclosed |
| US-10423033-B2 | Method for producing liquid crystal alignment film and liquid crystal display element using same | DIC CORPORATION (JP) | 2019-09-24 | — | — | US | disclosed |
| US-10287291-B2 | Seco-cyclopropapyrroloindole compounds, antibody-drug conjugates thereof, and methods of making and use | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-05-14 | — | — | US | disclosed |
| US-20180051031-A1 | SECO-CYCLOPROPAPYRROLOINDOLE COMPOUNDS, ANTIBODY-DRUG CONJUGATES THEREOF, AND METHODS OF MAKING AND USE | THE SCRIPPS RESEARCH INSTITUTE | 2018-02-22 | — | — | US | disclosed |
| US-9856210-B2 | Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis | KYOTO UNIVERSITY (JP) | 2018-01-02 | — | — | US | disclosed |
| WO-2005089747-A1 | NOVEL AZABICYCLIC DERIVATIVES, PREPARATION METHOD THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2005-09-29 | — | — | WO | disclosed |
| WO-2005035627-A1 | WATER-SOLUBLE POLYHYDROXYAMINOETHER AND PROCESS FOR PREPARING THE SAME | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-04-21 | — | — | WO | disclosed |
| WO-1999018091-A1 | NOVEL COMPOUNDS USEFUL AS NEURO-PROTECTIVE AGENTS | ELI LILLY AND COMPANY (US) | 1999-04-15 | — | — | WO | disclosed |
| US-5516672-A | CONTAINING A BENZENE DERIVATIVE AS STABILIZER; MEDICAL DIAGNOSIS; STORAGE STABILITY | KONICA CORPORATION (JP) | 1996-05-14 | — | — | US | disclosed |
| EP-0345728-A2 | Dye composition for keratinous fiber | Kao Corporation (JP) | 1989-12-13 | — | — | EP | disclosed |
| US-4140836-A | PRIMERS, WATERPROOFING, ADHESION | PPG INDUSTRIES, INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4098740-A | PRIMER COATINGS, POLYEPOXIDES, PHENOLS | PPG INDUSTRIES, INC. (US) | 1978-07-04 | — | — | US | disclosed |
| US-4031051-A | Hydrolyzed reaction product of a polyepoxide with a phenolic compound having a group hydrolyzable to a carboxyl and curing agent therefor | PPG INDUSTRIES, INC. (US) | 1977-06-21 | — | — | US | disclosed |
| US-4009208-A | N,N'-HEPTAMETHYLENEBIS(4-METHOXYBENZAMIDE) | STERLING DRUG INC. (US) | 1977-02-22 | — | — | US | disclosed |
| US-3960795-A | Hydrolyzed reaction product of a polyepoxide with a phenolic compound having a group hydrolyzable to carboxyl | PPG INDUSTRIES, INC. (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200102264-A1 | MARMELIN ANALOGS AND METHODS OF USE IN CANCER TREATMENT | COIL, MUC1, MAN2B2 | GFER 4658/4885MPO 3183/4885CYP3A4 1680/4885 |
| US-20230128688-A1 | DIRECTED CONJUGATION TECHNOLOGIES | CD2BP2, CD2, CD47 | GFER 1452/4885MPO 743/4885CYP3A4 3661/4885 |
| US-20180051031-A1 | SECO-CYCLOPROPAPYRROLOINDOLE COMPOUNDS, ANTIBODY-DRUG CONJUGATES THEREOF, AND METHODS OF MAKING AND USE | CD22, GDI2, GDI1 | GFER 653/4885MPO 2170/4885CYP3A4 312/4885 |
| US-10287291-B2 | Seco-cyclopropapyrroloindole compounds, antibody-drug conjugates thereof, and methods of making and use | CD22, GDI2, GDI1 | GFER 653/4885MPO 2170/4885CYP3A4 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.