Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9625360 | 0.84 | RIPK1 (0.39) | KIF11RIPK1HPGDKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9626820 | 0.84 | HPGD (0.38) | MEN1KMT2AHTTKIF11RIPK1 | |
| Oxalic Acid SCHEMBL9624956 | 0.82 | BLM (0.35) | FFAR1KIF11RIPK1HPGDKDM4E | |
| Oxalic Acid SCHEMBL9625441 | 0.81 | DPP4 (0.44) | KIF11EPHX1KDM4EALDH1A1 | |
| SCHEMBL9625078 | 0.79 | RIPK1 (0.41) | KIF11RIPK1POLBHPGDKDM4E | |
| Oxalic Acid SCHEMBL9625643 | 0.78 | ITGB3 (0.38) | POLBEPHX1KDM4E | |
| Oxalic Acid SCHEMBL9625240 | 0.77 | KDM4E (0.39) | FFAR1KMT2AKIF11RIPK1HPGD | |
| SCHEMBL9625071 | 0.77 | RIPK1 (0.37) | FFAR1HTTKIF11RIPK1HPGD | |
| Oxalic Acid SCHEMBL9625351 | 0.76 | TDP1 (0.45) | RIPK1POLBHPGDKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9625642 | 0.76 | RIPK1 (0.43) | RIPK1POLBHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0322391-B1 | NEW PHENYLALKYLAMINE DERIVATIVES | AKTIEBOLAGET ASTRA (SE) | 1992-03-25 | — | — | EP | disclosed |
| EP-0322391-A1 | New phenylalkylamine derivatives | AKTIEBOLAGET ASTRA (SE) | 1989-06-28 | — | — | EP | disclosed |