Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11487733 | 0.98 | GPR35 (0.42) | GPR35ALOX15TSHRHIF1ALMNA | |
| SCHEMBL11487725 | 0.86 | LMNA (0.39) | GPR35LMNASMN1; SMN2MAPK1ALDH1A1 | |
| SCHEMBL11512309 | 0.84 | LMNA (0.38) | LMNASMN1; SMN2MAPK1ALDH1A1TP53 | |
| SCHEMBL11512311 | 0.84 | LMNA (0.48) | LMNASMN1; SMN2MAPK1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL11490077 | 0.81 | GPR35 (0.41) | GPR35ALOX15TSHRHIF1ALMNA | |
| SCHEMBL9626967 | 0.81 | SMN1; SMN2 (0.43) | LMNASMN1; SMN2MAPK1ALDH1A1TP53 | |
| SCHEMBL63292 | 0.80 | LMNA (0.50) | LMNASMN1; SMN2MAPK1ALDH1A1TP53 | |
| Hydrochloric Acid SCHEMBL10580491 | 0.79 | ALOX15 (0.39) | GPR35ALOX15TSHRHIF1ALMNA | |
| SCHEMBL1179309 | 0.76 | HCAR2 (0.38) | GPR35ALOX15TSHRHIF1ALMNA | |
| SCHEMBL1178799 | 0.73 | KDM4E (0.42) | ALOX15TSHRHIF1ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321784-B1 | FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0255890-B1 | PROCESS FOR THE REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0321784-A2 | Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials | BAYER AG (DE) | 1989-06-28 | — | — | EP | disclosed |
| US-4841030-A | Azo reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1989-06-20 | — | — | US | disclosed |
| EP-0151792-B1 | REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |
| EP-0158882-B1 | TRIPHENEDIOXAZINE DYES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| US-4695632-A | ANIONIC DYE AFFINITY | BAYER AKTIENGESELLSCHAFT (DE) | 1987-09-22 | — | — | US | disclosed |
| US-4621138-A | Triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-04 | — | — | US | disclosed |
| EP-0097289-B1 | AZO DYESTUFFS | BAYER AG (DE) | 1986-10-15 | — | — | EP | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4126609-A | AZO DYESTUFF WITH A FIBER-REACTIVE GROUP ATTACHED TO A NAPHTHALENE SULPHONIC ACID COMPONENT | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-21 | — | — | US | disclosed |
| US-4122079-A | Reactive azo dyestuffs from diazotized sulfo-amino naphthalenes and diaminosulfobenzenes | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-24 | — | — | US | disclosed |
| US-4118382-A | DYES FOR CELLULOSE, WOOL, SILK, POLYAMIDE, AND POLYURETHANE FIBERS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-10-03 | — | — | US | disclosed |
| US-4089895-A | COUPLER FOR AZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-16 | — | — | US | disclosed |
| US-4065446-A | Reactive dyestuffs containing urea alkylene linkage between chromophore and reactive radical | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-27 | — | — | US | disclosed |
| US-4049704-A | AZO REACTIVE DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-09-20 | — | — | US | disclosed |
| US-3989692-A | PHTHALOCYANINE DYES, WOOL, SILK, POLYAMIDES, CELLULOSE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3988310-A | FIBER-REACTIVE DYES; CELLULOSE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-10-26 | — | — | US | disclosed |
| US-3957751-A | WATER-SOLUBLE REACTIVE DYESTUFFS OF THE MONOAZO SERIES CONTAINING AN ACTIVE METHYLENE COUPLING COMPONENT | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-05-18 | — | — | US | disclosed |