Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | JUN | P05412 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | XPO1 | O14980 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATF1 | P18846 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7087131 | 0.81 | NFKB1 (0.37) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL9564847 | 0.78 | NFKB1 (0.36) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL9626014 | 0.75 | ALDH1A1 (0.33) | KDM4EALDH1A1L3MBTL1MEN1KMT2A | |
| SCHEMBL29796850 | 0.75 | ALDH1A1 (0.53) | NFKB1JUNNFKB2RELAKDM4E | |
| SCHEMBL121368 | 0.75 | ALDH1A1 (0.53) | NFKB1JUNNFKB2RELAKDM4E | |
| SCHEMBL2481483 | 0.75 | NFKB1 (0.46) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL3056707 | 0.72 | NFKB1 (0.55) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL10586621 | 0.70 | STK17B (0.34) | NFKB1JUNNFKB2RELAPIN1 | |
| SCHEMBL31456643 | 0.69 | LRRK2 (0.36) | NFKB1JUNNFKB2RELAXPO1 | |
| SCHEMBL19501788 | 0.69 | CSNK1A1 (0.38) | NFKB1JUNNFKB2RELAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0321784-B1 | FORMAZANE DYES CONTAINING HEAVY METALS, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING FIBROUS MATERIALS | BAYER AG (DE) | 1992-03-18 | — | — | EP | disclosed |
| EP-0255890-B1 | PROCESS FOR THE REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1990-08-29 | — | — | EP | disclosed |
| EP-0321784-A2 | Formazane dyes containing heavy metals, process for their preparation and their use in dyeing and printing fibrous materials | BAYER AG (DE) | 1989-06-28 | — | — | EP | disclosed |
| EP-0151792-B1 | REACTION OF AMINES WITH HETEROCYCLIC REACTIVE COMPOUNDS | BAYER AG (DE) | 1988-11-30 | — | — | EP | disclosed |
| EP-0255890-A1 | Process for the reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1988-02-17 | — | — | EP | disclosed |
| EP-0158882-B1 | TRIPHENEDIOXAZINE DYES | BAYER AG (DE) | 1987-12-16 | — | — | EP | disclosed |
| EP-0158882-A2 | Triphenedioxazine dyes | BAYER AG (DE) | 1985-10-23 | — | — | EP | disclosed |
| EP-0151792-A2 | Reaction of amines with heterocyclic reactive compounds | BAYER AG (DE) | 1985-08-21 | — | — | EP | disclosed |
| EP-0128316-A1 | Reactive disazo dyes | BAYER AG (DE) | 1984-12-19 | — | — | EP | disclosed |
| EP-0050266-B1 | REACTIVE DISAZO DYES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN DYEING AND PRINTING MATERIALS THAT CONTAIN HYDROXYL AND/OR NITROGEN | BAYER AG (DE) | 1984-10-03 | — | — | EP | disclosed |
| EP-0050266-A1 | Reactive disazo dyes, process for their preparation and their use in dyeing and printing materials that contain hydroxyl and/or nitrogen | BAYER AG (DE) | 1982-04-28 | — | — | EP | disclosed |
| EP-0047863-A2 | Reactive phthalocyanine hyes, process for their preparation and their use in dyeing materials containing hydroxyle groups and/or nitrogen | BAYER AG (DE) | 1982-03-24 | — | — | EP | disclosed |
| EP-0043411-A2 | Reactive disazo dyestuffs, process for their preparation and their use in dyeing and printing materials containing nitrogen and/or hydroxyle groups | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |
| EP-0001451-B1 | WATER-SOLUBLE AZO-PHTHALOCYANINE FIBRE-REACTIVE DYESTUFFS, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1981-09-23 | — | — | EP | disclosed |
| EP-0001629-B1 | WATER-SOLUBLE, FIBRE-REACTIVE, GREEN AZO-PHTHALOCYANINE DYESTUFFS, THEIR PREPARATION AND THEIR USE | CASSELLA Aktiengesellschaft (DE) | 1981-08-12 | — | — | EP | disclosed |
| EP-0021372-A2 | Copper complexes of disazo reactive dyestuffs | BAYER AG (DE) | 1981-01-07 | — | — | EP | disclosed |
| EP-0013936-A1 | Reactive azo dyestuffs, their preparation and their use in dyeing materials containing hydroxyl groups and amide groups | BAYER AG (DE) | 1980-08-06 | — | — | EP | disclosed |
| EP-0001614-A1 | Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation | CASSELLA Aktiengesellschaft (DE) | 1979-05-02 | — | — | EP | disclosed |
| EP-0001629-A1 | Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1979-05-02 | — | — | EP | disclosed |
| EP-0001451-A1 | Water-soluble azo-phthalocyanine fibre-reactive dyestuffs, their preparation and their use | CASSELLA Aktiengesellschaft (DE) | 1979-04-18 | — | — | EP | disclosed |