Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.56 |
| ▸ | MAOB | P27338 | 6/20 | 0.53 |
| ▸ | MAOA | P21397 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | PPARD | Q03181 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | RXRG | P48443 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626424 | 0.88 | MAOB (0.69) | FFAR1MAOBMAOAFFAR4ALOX5 | |
| SCHEMBL1848 | 0.84 | ALDH1A1 (0.60) | FFAR1MAOBMAOAMEN1KMT2A | |
| SCHEMBL11565973 | 0.79 | KMT2A (0.56) | FFAR1MAOBMAOAPPARGMEN1 | |
| SCHEMBL8194650 | 0.76 | FFAR1 (0.55) | FFAR1MAOAPPARGMEN1KMT2A | |
| SCHEMBL3891167 | 0.75 | PLAAT3 (0.57) | MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26455103 | 0.75 | LMNA (0.66) | FFAR1MEN1KMT2AKDM4ELMNA | |
| SCHEMBL10937896 | 0.75 | LMNA (0.57) | FFAR1MAOAMEN1KMT2AKDM4E | |
| SCHEMBL14951699 | 0.75 | L3MBTL1 (0.76) | FFAR1MAOAMEN1KMT2AKDM4E | |
| SCHEMBL6365360 | 0.75 | MAPT (0.57) | FFAR1MAOAPPARDMEN1KMT2A | |
| SCHEMBL6365554 | 0.75 | PARP10 (0.55) | FFAR1MAOBMAOAPPARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |