Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.67 |
| ▸ | RXRA | P19793 | 1/20 | 0.64 |
| ▸ | RXRB | P28702 | 1/20 | 0.64 |
| ▸ | RXRG | P48443 | 1/20 | 0.64 |
| ▸ | MAOB | P27338 | 7/20 | 0.63 |
| ▸ | MAOA | P21397 | 1/20 | 0.63 |
| ▸ | BRD4 | O60885 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628021 | 0.89 | SPHK2 (0.66) | SPHK2RXRARXRBRXRGMAOB | |
| SCHEMBL748869 | 0.84 | SPHK2 (0.81) | SPHK2MAOBBRD4NPC1RAB9A | |
| SCHEMBL16048236 | 0.83 | MAOB (0.81) | SPHK2RXRARXRBRXRGMAOB | |
| SCHEMBL29784197 | 0.79 | RXRA (1.00) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL6522344 | 0.79 | RXRA (1.00) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL8935322 | 0.78 | GID4 (0.71) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL365474 | 0.78 | MAOB (0.67) | RXRARXRBRXRGMAOBMAOA | |
| SCHEMBL10186209 | 0.78 | RXRA (0.55) | SPHK2RXRARXRBRXRGMAOB | |
| SCHEMBL2655430 | 0.78 | S1PR1 (0.55) | SPHK2RXRARXRBRXRGMAOB | |
| SCHEMBL8935243 | 0.78 | GID4 (0.74) | RXRARXRBRXRGMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |