Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 2/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | TACR2 | P21452 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SHBG | P04278 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9626599 | 0.81 | MGLL (0.36) | AAK1SLC6A4 | |
| SCHEMBL9628202 | 0.79 | MAOB (0.54) | — | |
| SCHEMBL11235133 | 0.77 | HSD17B10 (0.43) | SLC6A3ALDH1A1LMNAHIF1AHSD17B10 | |
| SCHEMBL7603010 | 0.76 | MAPT (0.42) | SLC6A3HSD17B10ACHE | |
| SCHEMBL8476620 | 0.76 | MAPT (0.42) | SLC6A3HSD17B10ACHE | |
| SCHEMBL86328 | 0.75 | TDP1 (0.38) | AAK1CTSK | |
| SCHEMBL12734604 | 0.75 | CTSK (0.42) | CTSSCTSK | |
| SCHEMBL28100539 | 0.75 | CTSK (0.42) | CTSSCTSK | |
| SCHEMBL12734615 | 0.75 | CTSK (0.42) | CTSSCTSK | |
| SCHEMBL6514198 | 0.75 | TDP1 (0.38) | AAK1CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |