Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9628072 | 0.88 | MAOB (0.66) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL9626593 | 0.79 | KDM4E (0.43) | — | |
| SCHEMBL31703580 | 0.78 | ALOX5 (0.59) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL9628030 | 0.78 | MAOB (0.60) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL9626517 | 0.76 | FFAR1 (0.42) | MAOBALOX5PKMFFAR1 | |
| SCHEMBL9627382 | 0.75 | MAOB (0.63) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL9626408 | 0.74 | MAOB (0.57) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL9626343 | 0.73 | MAOB (0.67) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL9627603 | 0.73 | MAOB (0.56) | MAOBALOX5MAOARXRARXRB | |
| SCHEMBL31407768 | 0.73 | CTSL (0.43) | MAOBALOX5PKMFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0477184-A1 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INDUSTRIE ET SANTE (FR) | 1992-04-01 | — | — | EP | disclosed |
| WO-1990011997-A2 | INHIBITORS OF MONO-AMINE OXIDASE, PROCESS FOR THEIR PREPARATION, AND THEIR USE IN THERAPEUTICS. | FOURNIER INNOVATION ET SYNERGIE (FR) | 1990-10-18 | — | — | WO | disclosed |