Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.67 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.67 |
| ▸ | MMP2 | P08253 | 2/20 | 0.67 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.67 |
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | GMNN | O75496 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28423912 | 1.00 | PSMD14 (0.67) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL31426886 | 1.00 | PSMD14 (0.67) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL31472851 | 1.00 | PSMD14 (0.67) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| SCHEMBL5440695 | 0.98 | PSMD14 (0.63) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| SCHEMBL5447356 | 0.98 | PSMD14 (0.63) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Fluoride Ion SCHEMBL2398788 | 0.95 | PSMD14 (0.61) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL11227182 | 0.91 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL11875761 | 0.91 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL11215399 | 0.91 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BRAD52 | |
| Hydrochloric Acid SCHEMBL2912562 | 0.91 | PSMD14 (0.72) | PSMD14PLA2G1BMMP2ATG4BRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118931432-A | Polyurethane modified acrylic ester and vinyl acetate-acrylate copolymer emulsion adhesive thereof | 美邦（黄山）胶业有限公司 | 2024-11-12 | — | — | CN | claimed |
| CN-118307868-B | Packaging material and double-packaging bag | 湖南大道新材料有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-118307868-A | Packaging material and double-packaging bag | 湖南大道新材料有限公司 | 2024-07-09 | — | — | CN | claimed |
| CN-109880072-B | Self-catalyzed fast-curing pure polyester resin and preparation method and application thereof | 黄山市向荣新材料有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-112225888-A | Preparation method of pure polyester | 杭州临安华欣塑粉材料有限公司 | 2021-01-15 | — | — | CN | claimed |
| CN-118931432-A | Polyurethane modified acrylic ester and vinyl acetate-acrylate copolymer emulsion adhesive thereof | 美邦（黄山）胶业有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118931432-A | Polyurethane modified acrylic ester and vinyl acetate-acrylate copolymer emulsion adhesive thereof | 美邦（黄山）胶业有限公司 | 2024-11-12 | — | — | CN | disclosed |
| CN-118307868-B | Packaging material and double-packaging bag | 湖南大道新材料有限公司 | 2024-08-09 | — | — | CN | disclosed |
| CN-118307868-A | Packaging material and double-packaging bag | 湖南大道新材料有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-109880072-B | Self-catalyzed fast-curing pure polyester resin and preparation method and application thereof | 黄山市向荣新材料有限公司 | 2021-05-18 | — | — | CN | disclosed |
| CN-109880072-B | Self-catalyzed fast-curing pure polyester resin and preparation method and application thereof | 黄山市向荣新材料有限公司 | 2021-05-18 | — | — | CN | disclosed |
| EP-0068089-B2 | PROCESS FOR THE PREPARATION OF QUATERNARY AMMONIUM COMPOUNDS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1992-04-15 | — | — | EP | disclosed |
| EP-0068089-B1 | PROCESS FOR THE PREPARATION OF QUATERNARY AMMONIUM COMPOUNDS | Henkel Kommanditgesellschaft auf Aktien (DE) | 1986-12-30 | — | — | EP | disclosed |
| US-4492802-A | QUATERNIZATION OF TERTIARY AMINE WITH EPOXY COMPOUND | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1985-01-08 | — | — | US | disclosed |
| EP-0068089-A2 | Process for the preparation of quaternary ammonium compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-01-05 | — | — | EP | disclosed |
| EP-0068089-A2 | Process for the preparation of quaternary ammonium compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 1983-01-05 | — | — | EP | disclosed |