Fluoride Ion

Fluoride Ion

SCHEMBL2398788

CCCCCCCCCCC(O)C[N+](C)(C)C.[F-]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PSMD14 O00487 2/20 0.61
PLA2G1B P04054 2/20 0.61
MMP2 P08253 2/20 0.61
ATG4B Q9Y4P1 2/20 0.61
HSP90AA1 P07900 1/20 0.61
RAD52 P43351 1/20 0.61
GPR84 Q9NQS5 8/20 0.55
FFAR1 O14842 2/20 0.53
FFAR4 Q5NUL3 1/20 0.53
NFKB1 P19838 1/20 0.47
FDPS P14324 3/20 0.43
SPHK1 Q9NYA1 1/20 0.43
FAAH O00519 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5447356 0.98 PSMD14 (0.63) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
SCHEMBL5440695 0.98 PSMD14 (0.63) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL31426886 0.95 PSMD14 (0.67) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL31472851 0.95 PSMD14 (0.67) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL28423912 0.95 PSMD14 (0.67) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL9626985 0.95 PSMD14 (0.67) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Phosphoric Acid SCHEMBL23151879 0.90 PSMD14 (0.56) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
SCHEMBL3862567 0.88 PSMD14 (0.52) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL2912562 0.86 PSMD14 (0.72) PSMD14PLA2G1BMMP2ATG4BHSP90AA1
Hydrochloric Acid SCHEMBL11227182 0.86 PSMD14 (0.72) PSMD14PLA2G1BMMP2ATG4BHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3463584-B1 THERAPEUTIC DENTAL PASTES AND THE APPLICATION THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-12-27 EP disclosed
US-20230293393-A1 NATURAL TOOTH POWDER TABLETS MCCORMICK LINDSAY (US) 2023-09-21 US disclosed
US-11701306-B2 Natural tooth powder tablets MCCORMICK LINDSAY (US) 2023-07-18 US disclosed
US-11696879-B2 Therapeutic dental pastes and related methods and kits 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-07-11 US disclosed
US-20220211603-A1 Oral Compositions And Methods Of Use SOLVENTUM INTELLECTUAL PROPERTIES COMPANY 2022-07-07 US disclosed
US-20220192953-A1 Oral Compositions And Methods Of Use 3M INNOVATIVE PROPERTIES COMPANY 2022-06-23 US disclosed
CN-113840635-A Oral compositions and methods of use 3M创新有限公司 2021-12-24 CN disclosed
CN-113811282-A Oral compositions and methods of use 3M创新有限公司 2021-12-17 CN disclosed
CN-109152936-B Therapeutic toothpaste and related methods and kits 3M创新有限公司 2021-08-27 CN disclosed
WO-2020234811-A1 ORAL COMPOSITIONS AND METHODS OF USE 3M INNOVATIVE PROPERTIES COMPANY (US) 2020-11-26 WO disclosed
EP-0297212-A2 Oral compositions THE PROCTER & GAMBLE COMPANY (US) 1989-01-04 EP disclosed
US-4772461-A LIQUID DENTIFRICES, MOUTHWASH; ANTICALCULUS THE PROCTER & GAMBLE COMPANY (US) 1988-09-20 US disclosed
US-4684518-A ANTICALCULUS, PYROPHOSPHATE AND FLUORIDE THE PROCTER & GAMBLE COMPANY (US) 1987-08-04 US disclosed
US-4590066-A DENTRIFRICE CONTAINING PYROPHOSPHATES THE PROCTER & GAMBLE COMPANY (US) 1986-05-20 US disclosed
US-4515772-A ANTICARIES TOOTHPASTE THE PROCTER & GAMBLE COMPANY (US) 1985-05-07 US disclosed
US-4051234-A BIS-GUANIDINE COMPOUND, ETHYLENEDIAMINEDIACETIC ACID OR SALT AS CHELATOR THE PROCTER & GAMBLE COMPANY (US) 1977-09-27 US disclosed
US-4025616-A Oral compositions for plaque, caries and calculus retardation with reduced staining tendencies THE PROCTER & GAMBLE COMPANY (US) 1977-05-24 US disclosed
US-3959458-A PHOSPHONATE OR AMINO-PHOSPHORUS COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-05-25 US disclosed
US-3937807-A BISBIGUANIDE COMPOUND THE PROCTER & GAMBLE COMPANY (US) 1976-02-10 US disclosed
US-3934002-A BIS-GUANIDE THE PROCTER & GAMBLE COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11696879-B2 Therapeutic dental pastes and related methods and kits PROC, DNASE1, COL2A1 PSMD14 3985/4885PLA2G1B 1440/4885MMP2 58/4885
US-20220211603-A1 Oral Compositions And Methods Of Use MSR1, GCK, TAS2R40 PSMD14 2088/4885PLA2G1B 414/4885MMP2 2028/4885
US-20220192953-A1 Oral Compositions And Methods Of Use HRH2, HRH3, HRH4 PSMD14 2648/4885PLA2G1B 351/4885MMP2 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.