Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 10/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19028138 | 0.77 | MGLL (0.57) | MGLLTSHRCYP2D6USP2CYP3A4 | |
| SCHEMBL9627253 | 0.75 | LMNA (0.54) | NPC1RAB9AHTTCYP2D6CYP2C19 | |
| SCHEMBL4611641 | 0.75 | HIF1A (0.69) | RAB9ATSHRCYP2D6HSD17B10USP2 | |
| SCHEMBL9627863 | 0.72 | MGLL (0.45) | MGLLHTTCYP2D6USP2CYP3A4 | |
| SCHEMBL5003118 | 0.72 | HIF1A (0.69) | TSHRCYP2D6HSD17B10USP2CYP3A4 | |
| SCHEMBL3634940 | 0.72 | HPGD (0.60) | NPC1RAB9AHTTCYP2D6USP2 | |
| SCHEMBL3169203 | 0.71 | MGLL (0.46) | MGLL | |
| SCHEMBL9674597 | 0.70 | MAPT (0.57) | NPC1RAB9ATSHRHTTSMN1; SMN2 | |
| SCHEMBL8132365 | 0.69 | NLRP3 (0.60) | DPP7CYP2D6HSD17B10CYP3A4CYP2C9 | |
| SCHEMBL8127758 | 0.69 | DPP7 (0.54) | DPP7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112385-A | Useful in rice paddies | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0268688-B1 | SUBSTITUTED ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-03-04 | — | — | EP | disclosed |
| US-4968341-A | PRE-AND POSTEMERGENCE HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0268688-A1 | SUBSTITUTED ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-06-01 | — | — | EP | disclosed |