Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579775 | 0.98 | MAPT (0.58) | MAPTNPSR1POLBALDH1A1KMT2A | |
| SCHEMBL10487677 | 0.73 | KMT2A (0.55) | MAPTNPSR1ALDH1A1KMT2ARAB9A | |
| SCHEMBL9627265 | 0.70 | MGLL (0.50) | RAB9ANPC1SMN1; SMN2HTTTSHR | |
| SCHEMBL9730741 | 0.69 | TSHR (0.42) | MAPTALDH1A1RAB9AHPGDTSHR | |
| SCHEMBL9627253 | 0.69 | LMNA (0.54) | MAPTNPSR1POLBALDH1A1KMT2A | |
| SCHEMBL3456204 | 0.68 | HSD11B1 (0.66) | MAPTNPSR1POLBALDH1A1KMT2A | |
| SCHEMBL29944043 | 0.68 | HSD11B1 (0.66) | MAPTNPSR1POLBALDH1A1KMT2A | |
| SCHEMBL9672914 | 0.67 | ALDH1A1 (0.43) | MAPTNPSR1POLBALDH1A1KMT2A | |
| SCHEMBL11003719 | 0.66 | ALDH1A1 (0.39) | MAPTALDH1A1 | |
| SCHEMBL15415403 | 0.65 | HTT (0.50) | POLBALDH1A1KMT2ARAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0270683-B1 | ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-09-09 | — | — | EP | disclosed |
| US-5112385-A | Useful in rice paddies | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1992-05-12 | — | — | US | disclosed |
| US-4968341-A | PRE-AND POSTEMERGENCE HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO. (JP) | 1990-11-06 | — | — | US | disclosed |
| EP-0270683-A1 | ARYLOXYUREAS, PROCESS FOR THEIR PREPARATION, AND THEIR USE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1988-06-15 | — | — | EP | disclosed |